Cellular Responses of MC3T3-E1 Mouse Osteoblast-Like Cells to Rough Surfaced Substrates
MC3T3-E1 mouse osteoblast-like cells were seeded at high cell density to form confluent monolayer on rough surfaced culture substrates. Osteoblastic gene and protein expressions and matrix mineralization were investigated to clarify the effect of surface roughness on differentiation of MC3T3-E1 cells.
Guy Daculsi and Pierre Layrolle
T. Saito et al., "Cellular Responses of MC3T3-E1 Mouse Osteoblast-Like Cells to Rough Surfaced Substrates", Key Engineering Materials, Vols. 361-363, pp. 1071-1074, 2008