Comparison of the Biological Behavior of Wollastonite Bioceramics Prepared from Synthetic and Natural Precursors

Ana Maria Minarelli Gaspar; Sybele Saska; L.R. da Cunha; P.D.A. Bolini; R. García Carrodeguas; Antonio de Aza; P. Pena; P.N. De Aza; S. De Aza

doi:10.4028/www.scientific.net/KEM.361-363.1083

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HomeKey Engineering MaterialsKey Engineering Materials Vols. 361-363Comparison of the Biological Behavior of...

Comparison of the Biological Behavior of Wollastonite Bioceramics Prepared from Synthetic and Natural Precursors

Abstract:

Wollastonite bioceramics prepared from synthetic and natural precursors were implanted in rats in bone and subcutaneous tissues. The implant sites were excised after 7, 30 and 120 days, fixed, dehydrated, embedded in paraffin wax for serial cutting and examined under transmitted light microscope. It was found a very similar behavior for both wollastonite bioceramics. They were biocompatible, bioactive and biodegradable when implanted in rat bone. The synthetic ceramic was more reabsorbable than the one from natural powder. When implanted in subcutaneous rat tissue, both materials elicited a mild initial inflammatory reaction that practically disappeared after 120 days. Both materials were encapsulated with a very thin fibrous capsule and slightly reabsorbed at their surfaces. None of the materials induced ectopic osteogenesis. According to the results, the studied materials seem to be able for manufacturing reabsorbable bone implants.

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Periodical:

Key Engineering Materials (Volumes 361-363)

Pages:

1083-1086

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.361-363.1083

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Online since:

November 2007

Authors:

Ana Maria Minarelli Gaspar, Sybele Saska, L.R. da Cunha, P.D.A. Bolini, R. García Carrodeguas, Antonio de Aza, P. Pena, P.N. De Aza, S. De Aza

Keywords:

Biocompatibility, Calcium Phosphate, In Vitro Test, Wollastonite

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References

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