Preparation of the Hydroxyapatite/Collagen Three-Dimensional Scaffold from its Membrane

Abstract:

Effect of osteogenic activities of MG63 on the HAp/Col membrane was examined at day 10 and 14 by reverse-transcript and real-time polymerase chain reactions. Osteogenic activities of MG63 were upregulated by culture them on the HAp/Col membrane in comparison to those on tissue culture polystyrene. The novel three-dimensional HAp/Col scaffold was prepared from the HAp/Col wavy membrane. The cylindrical HAp/Col scaffold was successfully prepared and indicated at least 2.5-times higher compressive strength and Young's modulus compared to the previous HAp/Col composites. The novel scaffold could be useful for regenerative medicine.

• Periodical: Key Engineering Materials (Volumes 361-363)
• Pages: 431-434
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.361-363.431
• Online since: November 2007
• Authors: Masanori Kikuchi
• Keywords: Collagen, Hydroxyapatite (HAP), Membrane, Nanocomposite, Scaffold

References

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