Sol-Gel Synthesis and In Vitro Cell Compatibility Analysis of Silicate-Containing Biodegradable Hybrid Gels

Kanji Tsuru; Z. Robertson; B. Annaz; Iain R. Gibson; Serena Best; Yuki Shirosaki; Satoshi Hayakawa; Akiyoshi Osaka

doi:10.4028/www.scientific.net/KEM.361-363.447

Paper Titles

Preparation of the Hydroxyapatite/Collagen Three-Dimensional Scaffold from its Membrane
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Calcium Phosphate Mineralized GBR Membranes: Preparation and Properties
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Macro/Microporous Biphasic Calcium Phosphate Cylinders and Resorbable Collagen Membranes for Guided Bone Growth
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Porous Hydroxyapatite Surface-Modified by Polypyrrole-Heparin Conducting Polymer
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Sol-Gel Synthesis and In Vitro Cell Compatibility Analysis of Silicate-Containing Biodegradable Hybrid Gels
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Modified Poly-ε-Caprolactone (PCL) with Phosphorous Containing Compounds for Biomineralization
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Formation of an FGF-2-Apatite Composite Layer on Ethylene-Vinyl Alcohol Copolymer
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Apatite Formation on α-Tricalcium Phosphate/Poly(D,L-Lactide-Co-Glycolide) Nanocomposite
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Preparation and Evaluation of Nano-Hydroxyapatite/β-Tricalcium Phosphate/Chitosan Composite Scaffolds for Bone Tissue Engineering
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HomeKey Engineering MaterialsKey Engineering Materials Vols. 361-363Sol-Gel Synthesis and In Vitro Cell Compatibility...

Sol-Gel Synthesis and In Vitro Cell Compatibility Analysis of Silicate-Containing Biodegradable Hybrid Gels

Abstract:

Novel hybrid gels in the system gelatin-GPTMS-TEOS were prepared via a sol-gel route, and their ability to release Si(IV) was examined using MG63 osteoblast-like cell culture. The amount of Si released and the release rate were controllable by changing the mixing ratio of GPTMS and TEOS. In addition, the hybrids had biocompatible surfaces. It is expected that the hybrids will be utilized for the investigation of the effect of Si on cell differentiation and tissue regeneration.

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Periodical:

Key Engineering Materials (Volumes 361-363)

Pages:

447-450

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.361-363.447

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Online since:

November 2007

Authors:

Kanji Tsuru, Z. Robertson, B. Annaz, Iain R. Gibson, Serena Best, Yuki Shirosaki, Satoshi Hayakawa, Akiyoshi Osaka

Keywords:

Biodegradability, Cell Material Interactions, Organic-Inorganic Hybrid, Scaffold, Tissue Engineering

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References

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