Effect of Saline Precipitation on the Production of Collagen-Hydroxyapatite (1:1 wt%) Composite

Doris M. Campos; Lídia Ágata de Sena; Gloria Dulce  de Almeida Soares

doi:10.4028/www.scientific.net/KEM.396-398.425

Paper Titles

Bovine Hydroxyapatite (BHA) Boron Oxide Composites
p.403

Bovine Hydroxyapatite (BHA) Strontium Oxide Composites
p.407

Combustion Synthesis of Hydroxyapatite and Hydroxyapatite (Silver) Powders
p.411

Development of Gelatin/HA Membranes
p.421

Effect of Saline Precipitation on the Production of Collagen-Hydroxyapatite (1:1 wt%) Composite
p.425

Effect of Storage Conditions on Biaxial Flexure Strengths of MTA
p.429

Fabrication of Bioactive Organic Polymer by Using Apatite Nuclei-Contained Inorganic Binder
p.433

Fibroin-Based Material from Natural Silk Can Be Associated with Alginate and Mesenchymal Progenitor Cells
p.437

Hydroxyapatite-Sheet Microstructure of Shinbone
p.441

HomeKey Engineering MaterialsKey Engineering Materials Vols. 396-398Effect of Saline Precipitation on the Production...

Effect of Saline Precipitation on the Production of Collagen-Hydroxyapatite (1:1 wt%) Composite

Abstract:

Composites based on hydroxyapatite (HA) and collagen are being used for bone engineering applications. Synthetic composites were produced by precipitating hydroxyapatite in a reaction medium containing collagen fibers. The effect of saline treatment during the procedure of fibrils extraction on the composite morphology, phases presented and in vitro stability was evaluated. The FTIR analysis showed collagen bands well preserved. By Rietveld analysis, additional peaks of sodium chloride were identified on sample made from collagen submitted to saline precipitation. Besides that, the mineral formed phase is a carbonated apatite. This step during fibrils extraction results in larger areas of collagen uncoated and higher stability in culture medium. Despite of this, a cross-linking agent will be necessary to maintain the composite in culture for longer times.

You might also be interested in these eBooks

View Preview

Info:

Periodical:

Key Engineering Materials (Volumes 396-398)

Pages:

425-428

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.396-398.425

Citation:

Cite this paper

Online since:

October 2008

Authors:

Doris M. Campos, Lídia Ágata de Sena, Gloria Dulce de Almeida Soares

Keywords:

Hydroxyapatite (HAP), In Vitro Fibrillogenesis, Type I Collagen

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

References

[1] M. Kikuchi, T. Ikoma, S. Itoh, H.N. Matsumoto, Y. Koyama, K. Takakuda, K. Shinomiya, J. Tanaka: Composites Science and Technology, Vol. 64 (2004a), pp.819-825.

DOI: 10.1016/j.compscitech.2003.09.002

Google Scholar

[2] S.J. Kalita, A. Bhardwaj, H.A. Bhatt: Materials Science and Engineering C, Vol. 27 (2006), pp.441-449.

Google Scholar

[3] S. Kannan, A. Balamurugan, S. Rajeswari: Trends in Biomaterials & Artificial Organs, Vol. 14 (2001), Issue. 2, pp.30-36.

Google Scholar

[4] S.M. Cool, M.R. Forwood, P. Campbell, M.B. Bennet.: Bone, Vol. 30, Issue 2 (2002), p.382392.

Google Scholar

[5] L.A. Sena, P. Serricella, R. Borojevic, A.M. Rossi, G.A. Soares: Key Engineering Materials, Vol. 254 (2004), pp.493-496.

DOI: 10.4028/www.scientific.net/kem.254-256.493

Google Scholar

[6] Y. Zhai, F.Z. Cui, Y. Wang: Current Applied Physics, Vol. 5 (2005), pp.429-432.

Google Scholar

[7] A. Tachibana, S. Kaneko, T. Tanabe, K. Yamauchi: Biomaterials, Vol. 26 (2005), pp.297-302.

Google Scholar

[8] D. Scharnweber, R. Born, K. Flade, S. Roessler, M. Stoelzel, H. Worch: Biomaterials, Vol. 25 (2004), pp.2371-2380.

DOI: 10.1016/j.biomaterials.2003.09.025

Google Scholar