Constructing Phylogenetic Tree Based on Three-Parameter Model

Article Preview

Abstract:

Neighbor Joining Algorithm (Neighbor-Joining or NJ) is a common way to construct phylogenetic trees. To enhance the accuracy of constructing the phylogenetic trees, we use the Kimura three-parameter model to calculate the distance between sequences, raising a way to improve NJ. By computer simulation, we made a comparative analysis of the accuracy among the improved NJ, UPGMA, and the original NJ, the result showing that the improved NJ is superior to UPGMA and the original NJ.

You might also be interested in these eBooks

Info:

Periodical:

Key Engineering Materials (Volumes 474-476)

Pages:

2193-2197

Citation:

Online since:

April 2011

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2011 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

[1] LI Yu-jian XU Li-ye. Improvement for Unweighted Pair Group Method With Arithmetic Mean and Its Application; Journal of Beijing University of Technology; 2007-12. (in Chinese).

Google Scholar

[2] LI Yu-jian Gao kai. An Improved Neighbor-Joining Method and Its Applications; Journal of Beijing University of Technology; 2009-2. (in Chinese).

Google Scholar

[3] Saitou N, Nei M. The Neighbor-Joining Method : a new method for reconstructing phylogenetic trees. Mol. Biol. Evol. 1987, 4(4): 406-425.

Google Scholar

[4] Motoo Kimura. Estimation of evolutionary distances between homologous nucleotide sequences. Proceeding of the National Academy of Science Vol. 78. NO. 1, PP. 454-458, January (1981).

DOI: 10.1073/pnas.78.1.454

Google Scholar

[5] Cai lu. Bioinformatics. Beijing, Chemical Industry Press, 2006. 12 190-206. (in Chinese).

Google Scholar

[6] Tan Yanfang Jin Renchao. The Efficient Algorithm for Reconstructing Phylogenetic Tree Based on Neibor-joining Method; Computer Engineering and Applications; 2004-21. (in Chinese).

Google Scholar

[7] Zhuang Jun, Lin Giying. The Application of Poisson Distribution in Biology. Acta Laser Biology Sinica, 2007, 16(5): 655-658. (in Chinese).

Google Scholar