Permeability Characteristics of Human Dentin and a Porous Ceramic

Abstract:

Objectives: To compare the permeability of human dentin and a porous ceramic with two different compositions of perfusion fluid, in vitro. Methods: Dentin discs were cut from extracted third molar at a level close to the pulp chamber and ceramic discs were cut from a porous ceramic block. The convective permeability of the discs was measured in a fluid transport model using de-ionised water or 1:3 diluted bovine serum and the hydraulic conductance was determined. Results: In the negative controls, no flow was detected. The hydraulic conductance values for the dentin discs and the ceramic discs when water was used as the perfusion fluid were 0.069±0.023and 0.047±0.019ml min^-1 cm^-2 cm H₂O^-1, respectively. When the discs were perfused with the diluted bovine serum the mean (standard error of the mean) hydraulic conductance values for the dentin and the ceramic discs were 0.036±0.016 and 0.012±0.0055 ml min^-1 cm^-2 cm H₂O^-1, respectively. Conclusion: Basing on the modern technique it is possible to fabricate discs of hydroxylapatite ceramic to act as substitutes for dentin barriers in cytotoxicity test.

• Periodical: Key Engineering Materials (Volume 492)
• Pages: 501-504
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.492.501
• Online since: September 2011
• Authors: Xin Yi Zhao, Ya Ping Li, Shi Bao Li
• Keywords: Cytotoxicity Test, Human Dentin, Permeability, Porous Ceramics

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