Permeability Characteristics of Human Dentin and a Porous Ceramic
Objectives: To compare the permeability of human dentin and a porous ceramic with two different compositions of perfusion fluid, in vitro. Methods: Dentin discs were cut from extracted third molar at a level close to the pulp chamber and ceramic discs were cut from a porous ceramic block. The convective permeability of the discs was measured in a fluid transport model using de-ionised water or 1:3 diluted bovine serum and the hydraulic conductance was determined. Results: In the negative controls, no flow was detected. The hydraulic conductance values for the dentin discs and the ceramic discs when water was used as the perfusion fluid were 0.069±0.023and 0.047±0.019ml min-1 cm-2 cm H2O-1, respectively. When the discs were perfused with the diluted bovine serum the mean (standard error of the mean) hydraulic conductance values for the dentin and the ceramic discs were 0.036±0.016 and 0.012±0.0055 ml min-1 cm-2 cm H2O-1, respectively. Conclusion: Basing on the modern technique it is possible to fabricate discs of hydroxylapatite ceramic to act as substitutes for dentin barriers in cytotoxicity test.
Yiwang Bao, Danyu Jiang, Li Tian and Jianghong Gong
X. Y. Zhao et al., "Permeability Characteristics of Human Dentin and a Porous Ceramic", Key Engineering Materials, Vol. 492, pp. 501-504, 2012