Paper Titles

Fabrication of Chelate-Setting Cement Using Silicon-Substituted Hydroxyapatite and its Property
p.370

Antibacterial Activity In Vitro of the Developed Glass Ionomer Cements
p.375

Investigation of HA Cement Preparation and Properties by Using Central Composite Design
p.381

Solubility and Ingrowth Behaviour of Degradable and Figuline Calcium Alkaline Phosphate Cements
p.387

Improving the Bioactivity and Biocompatibility of Acrylic Cements by Collagen Coating
p.391

The Influence of Three Additives on the Setting Reaction Kinetics and Mechanical Strength Evolution of [Alpha]-Tricalcium Phosphate Cements
p.397

PH Evolution and Cytotoxicity of [Alpha]-Tricalcium Phosphate Cement with Three Different Additives
p.403

Mechanical Properties of Calcium Phosphate Cements (CPC) for Bone Substitution: Influence of Fabrication and Microstructure
p.409

Effect of Liquid/Powder Ratio on the Setting, Handling and Mechanical Properties of Collagen–Apatitic Cements
p.415

HomeKey Engineering MaterialsKey Engineering Materials Vols. 493-494Improving the Bioactivity and Biocompatibility of...

Improving the Bioactivity and Biocompatibility of Acrylic Cements by Collagen Coating

Article Preview

Abstract:

Polymer-ceramic composites based on polymethyl methacrylate are widely used in orthopaedics as suture materials and fixation devices due to their biocompatibility and ability to support bony growth (osteoconductive) and also bone bioactive (to form a calcium phosphate layer on its surface). The aim of this study is to compare the microstructure, bioactivity and biocompatibility of new acrylic cement containing silver and collagen coated, with a comercial one, by in vitro study in simulated body fluid. In order to evaluate the properties of the surface layer, SEM microscopy and ATR-FTIR spectroscopy are used. The results indicates that both silver content and the presence of collagen layer favourise the mineralisation process at the surface.

You might also be interested in these eBooks

Bioceramics 23

Info:

Periodical:

Key Engineering Materials (Volumes 493-494)

Pages:

391-396

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.493-494.391

Citation:

Cite this paper

Online since:

October 2011

Authors:

Simona Cavalu, Viorica Simon, Ipek Akin, G. Göller

Keywords:

Acrylic Cement, ATR FTIR, Bioactivity, Biocompatibility, Collagen Coating, SEM

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

© 2012 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

[1] L.L. Hench, Bioceramics, J. Am. Ceram. Soc. 81/7 (1998)1705.

[2] M. C. Rusu, D. L. Rusu, M. Rusu, Properties of acrylic bone cements formulated with PBMA, JOAM –Symposia 1/6 (2009)1020 – 1026.

[3] Y. He, J. P. Trotignon, B. Loty, A. Tcharkhtchi, J. Verdu, Effect of antibiotics on the properties of poly(methylmethacrylate)-based bone cement, J Biomed Mater Res. 63 (2002) 800.

DOI: 10.1002/jbm.10405

[4] H. Van de Belt, D. Neut, W. Schenk, J. R. Van Horn, H.C. Van der Mei, H. J. Busscher, Infection of orthopedic implants and the use of antibiotic-loaded bone cements. A review, Acta Orthop Scand. 72, (2001) 557.

DOI: 10.1080/000164701317268978

[5] R. Kumar, H. Munstedt, Silver ion release from antimicrobial polyamide/silver composites, Biomaterials 26, 14 (2004) (2081).

DOI: 10.1016/j.biomaterials.2004.05.030

[6] M. Kawashita, S. Tsuneyama, F. Miyaji,T. Kokubo, K. Yamamoto, Antibacterial silver-containing silica glass prepared by sol-gel method, Biomaterials 21 (2000) 393-398.

DOI: 10.1016/s0142-9612(99)00201-x

[7] E. Vernè, S. Di Nunzio, M. Bosetti, P. Appendino, C. Vitale Brovarone, G. Maina, M. Cannas, Surface characterization of silver-doped bioactive glass, Biomaterials, 26 (2005) 5111-5119.

DOI: 10.1016/j.biomaterials.2005.01.038

[8] Y. Fan, K. Duan, R. Wang, A composite coating by electrolysis-induced collagen self-assembly and calcium phosphate mineralization, Biomaterials 26, 14 ( 2005)1623-1632.

DOI: 10.1016/j.biomaterials.2004.06.019

[9] ** American Society for Testing and Materials (ASTM), Standard F451-99a, 2000 Annual Book of ASTM Standard, Vol. 13. 01 (2000) 55.

[10] S. Cavalu, V. Simon, F. Banica, In vitro study of collagen coating by elecrodeposition on acrylic bone cement with antimicrobial potential, Digest J. Nanomaterials and Biostructures, 6, 1 (2011) 87-97.

[11] T. Kokubo, S. Ito, Z. T. Huang, T. Hayashi, S. Sakka, T. Kitsugi, T. Yamamuro, Solutions able to reproduce in vivo surface-structure changes in bioactive glass-ceramic, J Biomed Mater Res 24, (1990) 331-343.

DOI: 10.1002/jbm.820240607

[12] S. Cavalu, V. Simon, C. Albon, C. Hozan, Bioactivity evaluation of new silver doped bone cement for prosthetic surgery, JOAM 9, 3 (2007) 693-697.

[13] S. Kale, S. Biermann, C. Edwards, C. Tarnowski, M. Morris, M. W. Long, Three-dimensional cellular development is essential for ex vivo formation of human bone, Nature Biotech 18 (2000) 954.

DOI: 10.1038/79439

[14] A. Tinti, P. Tadei, R. Simoni, C. Fagnano, Applications of vibrational spectroscopy to biomaterials, Asian J. Physics 15, 2 (2006) 267-273.

[15] S. Cavalu, S. Cîntă Pînzaru, N. Peica, G. Damian, W. Kiefer, Adsorption behavior of hyaluronidase onto silver nanoparticles and PMMA bone substitute, JOAM. 9, 3 (2007) 689-693.

[16] P. Sutandar, D. J. Ahn, E. I. Franses, FTIR ATR Analysis for Microstructure and Water Uptake in Poly (methylmethacrylate) Spin Cast and Langmuir-Blodgett Thin Films, Macromolecules 27 (1994) 7316 -7328.

DOI: 10.1021/ma00103a013

[17] M. Bellantone, H. D. Williams, L.L. Hench, Broad-Spectrum Bactericidal Activity of Ag2O-Doped Bioactive Glass , Antimicrobial Agents and Chemotherapy 46, 6 (2002)1940-(1945).

DOI: 10.1128/aac.46.6.1940-1945.2002

[18] S. Cavalu, V. Simon, G. Goller, I. Akin, Bioactivity and antimicrobial properties of PMMA/Ag2O acrylic bone cement collagen coated, Digest J. Nanomaterials and Biostructures, 6/2(2011) 87-97.