Experimental Research on Adjusting Cell Position and Orientation with Micro-Fluid

Article Preview

Abstract:

Position and orientation adjustment is an important issue in the micromanipulation of cells. A non-contact method based on micro-fluid for cell position and orientation control was introduced in this paper. The cells were positional fixed by the pressure force of a pair of lined micro-fluids from two tiny tubes. The orientation adjustment was realized by rotating cells in swirls caused by a pair of parallel micro-fluids. By spraying fluctuant micro-fluid, cells orientation can be controlled more precisely. The experiments proved that this non-contact cell position and orientation adjustment method is feasible and secure.

You might also be interested in these eBooks

Info:

Periodical:

Pages:

557-562

Citation:

Online since:

June 2012

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2012 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

[1] A. Fumihito, E. Toshiaki, Y. Ryuji, F. Toshio, 3D 6DOF manipulation of micro-object using laser trapped microtool, Proceedings - IEEE International Conference on Robotics and Automation (2006) 1390-1395.

DOI: 10.1109/robot.2006.1641903

Google Scholar

[2] K. Zhao, Some methods of dielectric study on small biological cells, Acta Biophysica. Sinica 16 (2000) 176-182.

Google Scholar

[3] A. Winkleman, K.L. Gudiksen, D. Ryan, G.M. Whitesides, A magnetic trap for living cells suspended in a paramagnetic buffer, Appl. Phys. Lett. 85 (2004) 2411-2413.

DOI: 10.1063/1.1794372

Google Scholar

[4] H. Aoyama, N. Chiba, O. Fuchiwaki, D. Misaki, T. Usuda, Non-contact bio cell manipulation by nonlinear micro flow around the vibrated pipette on micro robot, Twenty First American Society for Precision Engineering Annual Meeting. (2006).

Google Scholar

[5] G. Tian, L. Hou, W. Zhang, Mechanical analysis and experimental research on adjusting technology for cellular position and attitude in microinjection, China Mechanical Engineering 20 (2009) 409-412.

Google Scholar

[6] S. Floyd, C. Pawashe, M. Sitti, Two-dimensional contact and noncontact micromanipulation in liquid using an untethered mobile magnetic microrobot, Robotics. (2009) 1-11.

DOI: 10.1109/tro.2009.2028761

Google Scholar

[7] Q. Zhang, G. Su,W. Huang, China. Patent CN201020214553. 4. (2010).

Google Scholar