Radiological and Histological Evaluation of Regenos® which Implanted in Human Radial Fracture: A Clinical Case Report
Regenos® is a unidirectional porous hydroxyapatite (UDPHAp) bone substitutes, and the most distinctive feature of UDPHAp is its interconnected porous structure. We used Regenos® for the bone defect while distal radius fracture surgery with metal fixation implant. At six months post-operation, CT scans revealed the Regenos® implant was uniformly composed of cortical bone adjacent to the trabecular bone. At one-year postoperatively, we collected a sample of the implanted Regenos® while metal fixation plate removal surgery for histological evaluation. Regenos® implant sample revealed the presence of ossified bone stained green with Villanueva Goldner stain. Our findings demonstrate that Regenos® is a useful bone substitution material in the clinical setting.
Kunio Ishikawa and Yukihide Iwamoto
M. Iwasashi et al., "Radiological and Histological Evaluation of Regenos® which Implanted in Human Radial Fracture: A Clinical Case Report", Key Engineering Materials, Vols. 529-530, pp. 313-316, 2013