Hydrogen-Terminated Diamond Sensors for Electrical Monitoring of Cells

Tibor Izak; Katarína Novotná; Ivana Kopová; Lucie Bačáková; Marián Varga; Bohuslav Rezek; Alexander Kromka

doi:10.4028/www.scientific.net/KEM.605.577

Paper Titles

Fragmentation of Manganese Phthalocyanine Films by Laser Radiation
p.561

Ab Initio Study of Electronic Structure under Hydrostatic Pressure in Ferromagnetic Mn_xGe_1-x Alloy
p.565

FEM Simulation of Quartz Thickness Shear Mode Resonator for Gas Sensing Applications
p.569

Different Chemical Approaches for the Synthesis of Polyaniline Nanofibers and its Application in Ammonia Gas Sensing
p.573

Hydrogen-Terminated Diamond Sensors for Electrical Monitoring of Cells
p.577

Electrochemical Measurements of Phenothiazine Drugs in the Presence of Surface Active Ionic Liquids
p.581

Synthesis of ZnO Nanorod Arrays by Chemical Solution and Microwave Method for Sensor Application
p.585

Fabrication of Diamond Based Quartz Crystal Microbalance Gas Sensor
p.589

Morphology and Laser-Induced Photochemistry of Silicon and Nickel Nanoparticles
p.593

HomeKey Engineering MaterialsKey Engineering Materials Vol. 605Hydrogen-Terminated Diamond Sensors for Electrical...

Hydrogen-Terminated Diamond Sensors for Electrical Monitoring of Cells

Abstract:

In this paper we introduce fully optically transparent impedance biosensors based on intrinsic nanocrystalline diamond (NCD) films deposited on glass substrate. Prepared sensors have an interdigital electrode (IDE) structures realized by local hydrogen and oxygen termination of diamond surface, which mean in-plane configuration of active sensor area. Sensors were tested by real time monitoring of human osteoblast-like MG 63 cells in wide frequency range from 10 Hz to 100 kHz for several days. Two different measurement setups were used and compared regarding to their advantages and disadvantages. Proof of concept of diamond-based impedance sensor is showed, i.e. time dependence and frequency dependence (Nyquist plots) of absolute impedance.

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Periodical:

Key Engineering Materials (Volume 605)

Pages:

577-580

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.605.577

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Online since:

April 2014

Authors:

Tibor Izak, Katarína Novotná, Ivana Kopová, Lucie Bačáková, Marián Varga, Bohuslav Rezek, Alexander Kromka

Keywords:

Cell Cultivation, Diamond Thin Film, Impedance Measurements, Label-Free Biosensors, Real-Time Monitoring

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