Hybrid Hydrogels Intended as Scaffolds for Soft Tissue Repair

Abstract:

This work describes the investigation of the properties of hydrogels based on methacrylamide-modified gelatin (GelMA) and polyvinylpyrrolidone (PVP) with potential applications in wound treatment. While the semi-natural polymer insures the biocompatibility and biodegradability of the synthesized materials, the synthetic polymer was selected due to its water affinity and interesting mechanical properties. The efficiency of the polymerization process and the stability of the PVP within the semi interpenetrated polymer network (semiIPN) were verified through gel fraction study. The water affinity, tensile strength and rheological properties of the hydrogels were also investigated.

• Periodical: Key Engineering Materials (Volume 638)
• Pages: 54-61
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.638.54
• Online since: March 2015
• Authors: Andrada Serafim, Daniela G. Petre, Adriana Lungu, Horia Emil Cioflan, Izabela Cristina Stancu*
• Keywords: Mechanical Property, Methacrylamide-Modified Gelatin, Polyvinylpyrrolidone, Rheological Properties

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