Expansion Performance of Novel Balloon-Expandable Stent for Tapered Vessel

Abstract:

In-stent restenosis still remains an obsession to cardiologist, especially in tapered vessels. In this paper, we designed a novel balloon-expandable stent for tapered vessel and proposed a finite element method (FEM) to study the expansion of the novel stent. The effect of stent design parameters on stent tapering and foreshortening were also researched. Results show that the radial displacement of stent proximal end was always larger than that of stent distal end during stent expansion, and the stent had a tapered shape as a whole after expansion. The degree of stent tapering observed increased with the expansion pressure increase. Besides, increasing the gradient of ring amplitude not only could increase the tapering degree of stent after expansion, but also could decrease stent foreshortening, improving the positioning accuracy after stent implantation. In conclusion, FEM can quantify expansion performance of novel balloon-expandable stents and help designers to devise and assess new stent designs for tapered vessel.

• Periodical: Key Engineering Materials (Volumes 645-646)
• Pages: 1333-1338
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.645-646.1333
• Online since: May 2015
• Authors: Xiang Shen*, Yang Yang Sun, Bo Bo Wu
• Keywords: Balloon-Expandable Stent, Finite Element Method (FEM), Mechanical Property, Tapered Vessel

References

[1] W.M. Wilson, N.L.M. Cruden, Advances in coronary stent technology: current expectations and new developments, Research Reports in Clinical Cardiology 4 (2013) 85-96.

DOI: 10.2147/rrcc.s34408

[2] R.T. Higashida, P.M. Meyers, C. C. Phatouros, J.J. Connors, J.D. Barr, Reporting standards for carotid artery angioplasty and stent placement, J Vasc Interv Radiol 15 (2004) E1-E24.

DOI: 10.1097/01.rvi.0000128205.10925.8e

[3] G.R. Douglas, A.S. Phani, J. Gagnon, Analyses and design of expansion mechanisms of balloon expandable vascular stents, Journal of Biomechanics 47 (2014) 1438-1446.

DOI: 10.1016/j.jbiomech.2014.01.039

[4] S. Zhao, L. Gu, S.R. Froemming, On the importance of modeling stent procedure for predicting arterial mechanics, Journal of Biomechanical Engineering 134 (2012) 121005.

DOI: 10.1115/1.4023094

[5] H. Li, T. Qiu, B. Zhu, J. Wu, X. Wang, Design optimization of coronary stent based on finite element models, The Scientific World Journal 2013 (2013) 630243.

DOI: 10.1155/2013/630243

[6] K. Takashima, T. Kitou, K. Mori, Simulation and experimental observation of contact conditions between stents and artery models, Medical Engineering & Physics 29 (2007) 326-335.

DOI: 10.1016/j.medengphy.2006.04.003

[7] M. Zubaid, C. Bullr, G.J. Mancini, Normal angiographic tapering of the coronary arteries, Canadian Journal of Cardiology 18 (2002) 973-980.

[8] P. Datir, A.Y. Lee, S.D. Lamm, H.C. Han, Effects of geometric variations of the buckling of arteries, International Journal of Applied Mechanics 3 (2011) 385-406.

DOI: 10.1142/s1758825111001044

[9] L.H. Timmins, C.A. Meyer, M.R. Moreno, J.E. Moore, Mechanical modeling of stents deployed in tapered arteries. Ann Biomed Eng 36 (2008) 2042-(2050).

DOI: 10.1007/s10439-008-9582-0

[10] L.H. Timmins, M.W. Miller, F.J. Clubb, Increased artery wall stress post-stenting leads to greater intimal thickening, Laboratory Investigation 91 (2011) 955-967.

DOI: 10.1038/labinvest.2011.57

[11] M.S. Kim, L.S. Dean, In-stent restenosis, Cardiovascular Therapeutics 29 (2011) 190-198.