Synthesis of Silica Modified Large-Sized Hydroxyapatite Whiskers by a Hydrothermal Co-Precipitation Method

Abstract:

The objective of this study was to develop a novel silica modified large-sized hydroxyapatite whiskers with improved properties for use in bone repair applications. Large-sized whiskers with a mean length of 250μm were obtained by a hydrothermal co-precipitation method at 150°C, 7.5Mpa in high-pressure reactor. Silica modified hydroxyapatite whiskers were prepared by dissolving TEOS in ethanol solution, then sintering with hydroxyapatite. The compositional and morphological properties of prepared whiskers were studied by means of x-ray diffraction (XRD), Fouier transform infrared (FT-IR), scanning electron microscopy (SEM). The results indicated the evidence of nanosilicon dioxide particles on the surface of HAP whiskers. The size of nanosilicon dioxide particles depends on dropping and stirring rate. Hence, this new type of silica modified large-sized hydroxyapatite whiskers is a valuable candidate for biomedical applications.Key words: hydroxyapatite, hydrothermal co-precipitation, surface modified, whiskers

• Periodical: Key Engineering Materials (Volumes 645-646)
• Pages: 1339-1344
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.645-646.1339
• Online since: May 2015
• Authors: Yan Ting Yin, Qing Hua Chen, Ting Ting Yan, Qing Hua Chen*
• Keywords: Hydrothermal Co-Precipitation, Hydroxyapatite, Surface Modified, Whiskers

References

[1] Hongquan Zhang, Ming Zhang. Characterization and thermal behavior of calcium deficient hydroxyapatite whiskers with various Ca/P ratios[J]. Materials Chemistry and Physics, 2011, 126: 642-648.

DOI: 10.1016/j.matchemphys.2010.12.067

[2] Ruixue Sun, Kezheng Chen, Zhongmiao Liao, et al. Controlled synthesis and thermal stability of hydroxyapatite hierarchical microstructures[J]. Materials Research Bulletin, 2013, 48: 1143-1147.

DOI: 10.1016/j.materresbull.2012.12.013

[3] Lin KL, Chen L, Chang J. Fabrication of dense hydroxyapatite nanobioceramics with enhanced mechanical properties via two-step sintering process[J]. Int J Appl Ceram Technol, 2012, 9(3): 479-485.

DOI: 10.1111/j.1744-7402.2011.02654.x

[4] Bojan Jokic, Miodrag Mitric, Velimir Radmilovic, et al. Synthesis and characterization of monetite and hydroxyapatite whiskers obtained by a hydrothermal method[J]. Ceramics International, 2011, 37: 167-173.

DOI: 10.1016/j.ceramint.2010.08.032

[5] Suchanek W, Yashima M, Kakihana M, et al. Processing and mechanical preperties of hydroxyapatite reinforced with hydroxyapatite whiskersf[J]. Biomaterials, 1996, 17(17): 1715.

DOI: 10.1016/0142-9612(96)87652-6

[6] Wei G.C., Becher P.F. Toughening behavior in Sic-whisker-reinforced alumina[J]. J. Am. Ceram. Soc., 1994, 67(12): 267-269.

DOI: 10.1111/j.1151-2916.1984.tb19694.x

[7] Alieh Aminian, Mehran Solati-Hashjin, Ali Samadikuchaksaraei, et al. Synthesis of silicon-substituted hydroxyapatite by a hydrothermal method with two different phosphorous sources[J]. Ceramics International, 2011, 37: 1219-1229.

DOI: 10.1016/j.ceramint.2010.11.044

[8] Teshima K, Lee SH, Sakurai M, et al. Well formed one-dimensional hydroxyapatite crystals grown by an environmentally friendly flux method[J]. Cryst Growth Des, 2009, 9: 2937-40.

DOI: 10.1021/cg900159j

[9] Ramanan SR, Venkatesh R. A study of hydroxyapatite fibers prepared via sol-gel route[J]. Mater Lett, 2004, 58: 3320-3.

DOI: 10.1016/j.matlet.2004.06.030

[10] Li-Xia Yang, Jia-Jun Yin, Lu-Lu Wang, et al. Hydrothermal synthesis of hierarchical hydroxyapatite: Preparation, growth mechanism and drug release property[J]. Ceramics International, 2012, 38: 495–502.

DOI: 10.1016/j.ceramint.2011.07.033

[11] Soderhohn K.J. M Shang S.W. Molecular orientation of silane the surface of colloidal sillica[J]. J Dent Res, 1993, 72: 1050-1054.