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HomeKey Engineering MaterialsKey Engineering Materials Vol. 695Fibrin Sealants in Orthopaedic Surgery

Fibrin Sealants in Orthopaedic Surgery

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Abstract:

Due to its considerable systemic impact, several local and general methods to control surgical ( intra/perioperative) bleeding have been developed, with particular characteristics adapted to each type of surgery. In orthopaedic procedures, elective or urgent, bleeding is to be seriously considered , since usually both bones and soft tissues are injured or cut, so adapted haemostatic means have to be used. This issue is of particular importance especially when very small vessels are involved, and especially on large surfaces, since ligation or cauterization are useless in these situations. An effective tool in these circumstances is the group of fibrin sealants, which can stop diffuse bleeding on surfaces when produced by very small vessels. The authors present their clinical experience with fibrin sealants, underlining the indications and the limits of the method.

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Periodical:

Key Engineering Materials (Volume 695)

Pages:

99-105

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.695.99

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Online since:

May 2016

Authors:

Olivera Lupescu*, Mihail Nagea, Cristina Patru, Gheorghe Ion Popescu, Narcis Marcov

Keywords:

Fibrin Sealant, Haemostasis, Surgical Bleeding

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© 2016 Trans Tech Publications Ltd. All Rights Reserved

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[1] William D. Spotnitz, Fibrin Sealant: The Only Approved Hemostat, Sealant, and Adhesive—a Laboratory and Clinical Perspective, ISRN Surgery. Article ID 203943, (2014).

DOI: 10.1155/2014/203943

[2] W. D. Spotnitz, Fibrin sealant: past, present, and future: a brief review, World Journal of Surgery. 34 no. 4 (2010) 632–634.

DOI: 10.1007/s00268-009-0252-7

[3] J. Z. Young, P. B. Medawar, Fibrin suture of peripheral nerves. Measurement of the rate of regeneration, The Lancet. 236 (1940) 126–128.

DOI: 10.1016/s0140-6736(01)07978-8

[4] H. Matras, H. P. Dinges, H. Lassmann, B. Mamoli, Suture-free interfascicular nerve transplantation in animal experiments, Wiener Medizinische Wochenschrift. 122 (1972) 517–523.

[5] K. H. Siedentop, D. M. Harris, K. Ham, and B. Sanchez, Extended experimental and preliminary surgical findings with autologous fibrin tissue adhesive made from patient's own blood, Laryngoscope. 10 ( 1986) 1062–1064.

DOI: 10.1288/00005537-198610000-00003

[6] Associated Press, FDA Approves Nation's First Commercial Surgical Glue, Los Angeles Times, (1998).

[7] W. D. Spotnitz, P. D. Mintz, N. Avery, T. C. Bithell, S. Kaul, and S. P. Nolan, Fibrin glue from stored human plasma, An inexpensive and efficient method for local blood bank preparation. The American Surgeon. 8 (1987) 460–462.

[8] S. Prakas, A. Thakur, Platelet concentrates: past, present and future, Journal of Oral and Maxillofacial Surgery. 10 (2011) 45–49.

DOI: 10.1007/s12663-011-0182-4

[9] W. D. Spotnitz, R. Prabhu, Fibrin sealant tissue adhesive—review and update, Journal of Long-Term Effects of Medical Implants. 15 (2005) 245–270.

DOI: 10.1615/jlongtermeffmedimplants.v15.i3.20

[10] M. M. Lee, D. Jones, Applications of fibrin sealant in surgery, Surgical Innovation. 12 (2005) 203–213.

[11] M. Valbonesi, Fibrin glues of human origin, Best Practice and Research: Clinical Haematology, 19 (2006) 191–203.

DOI: 10.1016/j.beha.2005.01.009

[12] D. M. Albala, J. H. Lawson, Recent clinical and investigational applications of fibrin sealant in selected surgical specialties, Journal of theAmericanCollege of Surgeons. 202 (2006) 685–697.

DOI: 10.1016/j.jamcollsurg.2005.11.027

[13] C. Tabele, M. Montana, C. Curti et al., Organic glues or fibrin glues from pooled plasma: efficacy, safety and potential as scaffold delivery systems, Journal of Pharmacy and harmaceutical Sciences, 1 (2012) 124–140.

DOI: 10.18433/j39k5h

[14] H. C. Hedrich, M. Simunek, S. Reisinger et al., Fibrin chain cross-linking, fibrinolysis, and in vivo sealing efficacy of differently structured fibrin sealants, Journal of Biomedical Materials Research B. 100 (2012) 1507–1512.

DOI: 10.1002/jbm.b.32719

[15] Differences in biomechanical stability using various fibrin glue compositions for mesh fixation in endoscopic inguinal hernia repair, Surgical Endoscopy. 26 (2012) 3282–3286.

DOI: 10.1007/s00464-012-2339-8

[16] A. K. Dastjerdi, M. Pagano, M. T. Kaartinen, M. D. McKee, F. Barthelat, Cohesive behavior of soft biological adhesives: experiments and modeling, Acta Biomaterialia. 8 (2012) 3349–3359.

DOI: 10.1016/j.actbio.2012.05.005

[17] H. Kin, T. Nakajima, H. Okabayashi, Experimental study on effective application of fibrin glue, General Thoracic and Cardiovascular Surgery, 60 ( 2012) 140–144.

DOI: 10.1007/s11748-011-0864-3

[18] W. A. Curtin, G. J. Wang, N. C. Goodman, R. D. Abbott, W. D. Spotnitz, Reduction of hemorrhage after knee arthroplasty using cryo-based fibrin sealant, Journal of Arthroplasty. 14 (1999) 481–487.

DOI: 10.1016/s0883-5403(99)90105-5

[19] W. D. Spotnitz, S. Burks, Hemostats, sealants, and adhesives: components of the surgical toolbox, Transfusion. 7, (2008) 1502–1516.

DOI: 10.1111/j.1537-2995.2008.01703.x

[20] W.D. Spotnitz, S. Burks, Hemostats, sealants, and adhesives II: update as well as how and when to use the components of the surgical toolbox, Clinical and Applied Thrombosis/Hemostasis. 5 (2010) 497–514.

DOI: 10.1177/1076029610363589

[21] W.D. Spotnitz, S. Burks, Hemostats, sealants, and adhesives III: a new update as well as cost and regulatory considerations for components of the surgical toolbox, Transfusion. 10 (2012) 2243–2255.

DOI: 10.1111/j.1537-2995.2012.03707.x

[22] W. D. Spotnitz, Hemostats, sealants, and adhesives: a practical guide for the surgeon, TheAmerican Surgeon. 12 (2012) 1305–1321.

DOI: 10.1177/000313481207801221

[23] W.D. Spotnitz, S. Burks, Hemostats, sealants, and adhesives II: update as well as how and when to use the components of the surgical toolbox, Clinical and Applied Thrombosis/Hemostasis. 5 (2010) 497–514.

DOI: 10.1177/1076029610363589

[24] W. D. Spotnitz, Fibrin sealant in the United States: clinical use at the University of Virginia, Thrombosis and Haemostasis. 74 (1995) 482–485.

DOI: 10.1055/s-0038-1642725

[15] C. Schug-Pass, D. A. Jacob, H. Lippert,. Kockerling.

[25] G. J. Wang, D. S. Hungerford, C. G. Savory et al., Use of fibrin sealant to reduce bloody drainage and hemoglobin loss after total knee arthroplasty: a brief note on a randomized prospective trial, Journal of Bone and Joint Surgery A. 83 ( 2001) 1503–1505.

DOI: 10.2106/00004623-200110000-00007

[26] G. -J. Wang, C. A. Goldthwaite Jr., S. G. Burks et al., Experience improves successful use of fibrin sealant in total knee arthroplasty: implications for surgical education. Journal of Long-Term Effects of Medical Implants. 13 ( 2003) 389–397, (2003).

DOI: 10.1615/jlongtermeffmedimplants.v13.i5.40

[27] G. -J. Wang, C. A. Goldthwaite Jr., S. Burks et al., Fibrin sealant reduces perioperative blood loss in total hip replacement, Journal of Long-Term Effects of Medical Implants. 5 (2003) 399–411.

DOI: 10.1615/jlongtermeffmedimplants.v13.i5.50

[28] M. Schwartz, J. Madariaga, R. Hirose et al., Comparison of a new fibrin sealant with standard topical hemostatic agents, Archives of Surgery. 11 (2004) 1148–1154.

DOI: 10.1001/archsurg.139.11.1148

[29] R. Sherman, W. C. Chapman, G. Hannon, J. E. Block, Control of bone bleeding at the sternum and iliac crest donor sites using a collagen-based composite combined with autologous plasma: results of a randomized controlled trial, Orthopedics. 2 (2001).

DOI: 10.3928/0147-7447-20010201-16

[30] L. Sabatini, A. Trecci, D. Imarisio et al., Fibrin tissue adhesive reduces postoperative blood loss in total knee arthroplasty, Journal ofOrthopaedics and Traumatology. 3 (2012) 145–151.

DOI: 10.1007/s10195-012-0198-7

[31] A. Notarnicola, L. Moretti, A. Martucci et al., Comparative efficacy of different doses of fibrin sealant to reduce bleeding after total knee arthroplasty, Blood Coagulation & Fibrinolysis. 4 (2012) 278–284.

DOI: 10.1097/mbc.0b013e3283518846

[32] T. L. Bernasek, R. B. Burris, H. Fujii, M. F. Levering, J. A. Polikandriotis, J. J. Patterson, Effect on blood loss and costeffectiveness of pain cocktails, platelet-rich plasma, or fibrin sealant after total knee arthroplasty, Journal ofArthroplasty. 8 (2012).

DOI: 10.1016/j.arth.2012.02.018

[33] P. Massin, C. Scemama, C. Jeanrot, P. Boyer, Does fibrin sealant use in total knee replacement reduce transfusion rates? A non-randomised comparative study, Orthopaedics and Traumatology: Surgery and Research. 2 (2012) 180–185.

DOI: 10.1016/j.otsr.2011.10.012

[34] T. Dehne, R. Zehbe, J. P. Kr¨uger et al., A method to screen and evaluate tissue adhesives for joint repair applications, BMC Musculoskeletal Disorders. 13 (2012) article 175.

DOI: 10.1186/1471-2474-13-175