Quantitative Estimation of Connectivity among Pores in the Hydroxyapatite Scaffold Prepared by Slip Casting with Porogen

Min Chul Lee; Tai Joo Chung; Kyung Sik Oh

doi:10.4028/www.scientific.net/KEM.696.192

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HomeKey Engineering MaterialsKey Engineering Materials Vol. 696Quantitative Estimation of Connectivity among...

Quantitative Estimation of Connectivity among Pores in the Hydroxyapatite Scaffold Prepared by Slip Casting with Porogen

Abstract:

The connectivity of pores in the hydroxyapatite scaffold was quantitatively estimated by the infiltration of a setting resin in the scaffold and was evaluated by counting the number of pores filled with resin. As pore filled resin indicated the connection with at least one neighboring pore and outside, the volume fraction of the filled pores corresponded to the connectivity previously defined. For the specimen with 88% of connectivity, the scaffold successfully showed cellular migration and bone growth even at the deep part of the scaffold by the in vivo test. Thus, the connectivity evaluated in this study is a useful criterion for the prediction of successful cellular migration.

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Periodical:

Key Engineering Materials (Volume 696)

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192-195

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https://doi.org/10.4028/www.scientific.net/KEM.696.192

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Online since:

May 2016

Authors:

Min Chul Lee, Tai Joo Chung, Kyung Sik Oh*

Keywords:

Connectivity, Hydroxyapatite, Porogen, Scaffold, Slip Casting

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References

[1] G. Lemon, Y. Reinwald, L. White, S. Howdlec, K. Shakesheff, J. King, Interconnectivity analysis of supercritical CO2-foamed scaffolds, Comput. Meth. Prog. Bio. 106 (2012) 139-49.

DOI: 10.1016/j.cmpb.2010.08.010

Google Scholar

[2] L. Andersson, A. Jones, M. Knackstedt, L. Bergstrom, Permeability, pore connectivity and critical pore throat control of expandable polymeric sphere templated macroporous alumina, Acta Mater. 59 (2011) 1239-48.

DOI: 10.1016/j.actamat.2010.10.056

Google Scholar

[3] K.S. Oh, F. Caroff, R. Famery, M.F. Sigot-Luizard, P. Boch, Preparation of TCP–TiO2 biocomposites and study of their compatibility, J. Euro. Ceram. Soc. 18 (1988) 1931-37.

DOI: 10.1016/s0955-2219(98)00132-0

Google Scholar

[4] S.M. Seo, D.M. Kim, T.J. Chung, J.J. Yoo, H.J. Kim, H.J. Chun, J.W. Jang, K.S. Oh, Effect of milling time on the viscosity of hydroxyapatite suspension, Curr. Appl. Phys. 12 (2012) S71-S75.

DOI: 10.1016/j.cap.2012.02.023

Google Scholar

[5] J.J. Yoo, H.J. Kim, S.M. Seo, K.S. Oh, Preparation of a hemiporous hydroxyapatite scaffold and evaluation as a cell-mediated bone substitute, Ceram. Int. 40 (2014) 3079-87.

DOI: 10.1016/j.ceramint.2013.09.138

Google Scholar