Flexural Strength and Cytotoxicity of ZCC, a Resin Modified Zinc-Calcium Liner Prototype

Abstract:

Objective: To investigate the flexural strength and cytotoxicity of ZCC, a resin modified zinc oxide-calcium carbonate liner prototype, compared with commercial dental liners. Materials and Methods: ZCC, Dycal, Ultra-Blend® plus (UB), and TheraCal LC® (TC) were evaluated for flexural strength. Six samples of each material were incubated in growth medium (10% fetal bovine serum supplemented DMEM) for 24 h. Primary human dental pulp cells were cultured in the conditioned medium from each sample, with growth media used as a control. Cytotoxicity was determined using an MTT assay. Data were analyzed by one-way ANOVA. The value of p<0.05 was considered significant. Results: UB had the highest flexural strength with Dycal presenting the lowest values (p<0.05). ZCC demonstrated significantly higher flexural strength values compared with those of TC and Dycal (p<0.05). The MTT assay indicated that Dycal conditioned media significantly reduced cell viability at 24 and 48 hours (p<0.05). There was no significant difference in viability between the control, ZCC, UB, and TC groups at 24 and 48 hours (p>0.05). Conclusion: ZCC met the requirements for flexural strength per ISO 9917-2:2010(E). There was no significant difference in viability between the control and ZCC group at 24 and 48 hours.

• Periodical: Key Engineering Materials (Volume 751)
• Pages: 649-656
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.751.649
• Online since: August 2017
• Authors: Pasutha Thunyakitpisal*, Nonglax Thunyakitpisal, Sirithan Jiemsirilers, Dujreutai Pongkao Kashima
• Keywords: Cytotoxicity, Dental Liner, Flexural Strength, Physical Properties

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