Paper Titles

Preparation and Evaluation of Spray-Dried Nano-Hydroxyapatite/Saccharide Complex for Oral Administration
p.124

Structural Characterization of Mg-0.5Ca-xY Biodegradable Alloys
p.129

Some Tribological Aspects of Mg-0.5Ca-xY Biodegradable Materials
p.136

CO₂ Laser Bonding of Silicate-Substituted Strontium Apatite on PEEK and Osteointegration on its Surface
p.145

Particulate Titania Coating on Poly(Dimethylsiloxane) Films for Improving Osteoconductive Ability
p.151

Effect of Crystalline Calcium Phosphate Coatings Prepared in an Aqueous Solution on Corrosion Resistance of Bioabsorbable Magnesium Alloy
p.158

Bioceramics are Not Bioinert: The Role of Oxide and Non-Oxide Bioceramics on the Oxidation of UHMWPE Components in Artificial Joints
p.165

Titanium Nitride Film on Titanium Film by Magnetron Sputtering Method
p.176

Changes in Surface Condition during Fabrication Process of Bioactive Apatite Nuclei Incorporated PEEK
p.182

HomeKey Engineering MaterialsKey Engineering Materials Vol. 782Particulate Titania Coating on...

Particulate Titania Coating on Poly(Dimethylsiloxane) Films for Improving Osteoconductive Ability

Article Preview

Abstract:

The cytocompatibility of the poly (dimethylsiloxane) (PDMS) surfaces can be improved by the coating with biomaterials. In this study, the methodology for the particulate titania (PT) coating on the PDMS film was investigated via the combined process of microfluidic synthesis system with spin-coating, leading to the one-step synthesis and coating. The PT was successfully deposited on the O₂-plasma-treated PDMS films by mixing titanium tetraisopropoxide, isopropyl alcohol, water and octadecylamine in a microfluidic reactor and subsequently dropping. The rotation speed in the spin-coating plays an important role in the PT morphologies and deposition amounts on the PDMS films. Through the detailed investigation, the efficient condition for adhering PT to PDMS as well as inducing apatite formation from simulated body fluid was successfully discovered.

You might also be interested in these eBooks

Bioceramics 30

Info:

Periodical:

Key Engineering Materials (Volume 782)

Pages:

151-157

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.782.151

Citation:

Cite this paper

Online since:

October 2018

Authors:

Tania Guadalupe Peñaflor Galindo, Kota Shiba, Motohiro Tagaya*

Keywords:

Amorphous Titania, Hydroxyapatite Formation, Osteoconductivity, Poly(Dimethylsiloxane)

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

© 2018 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

* - Corresponding Author

[1] S. Pinto, P. Alves, C.M. Matos, A.C. Santos, L.R. Rodrigues, J.A. Teixeira, M.H. Gil, Poly (dimethyl siloxane) surface modification by low pressure plasma to improve its characteristics towards biomedical applications, Colloids Surf. B Biointerfaces 81 (2010).

DOI: 10.1016/j.colsurfb.2010.06.014

[2] S. Sugiura, J.I. Edahiro, K. Sumaru, T. Kanamori, Surface modification of polydimethylsiloxane with photo-grafted poly (ethylene glycol) for micropatterned protein adsorption and cell adhesion, Colloids Surf. B Biointerfaces 63 (2008) 301–305.

DOI: 10.1016/j.colsurfb.2007.12.013

[3] A.Mata, A. J. Fleischman, S. Roy, Characterization of polydimethylsiloxane (PDMS) properties for biomedical micro/nanosystems, Biomed. Microdevices 7 (2005) 281–293.

DOI: 10.1007/s10544-005-6070-2

[4] F. Sarvi, Z. Yue, K. Hourigan, M.C. Thompson, P.P. Chan, Surface-functionalization of PDMS for potential micro-bioreactor and embryonic stem cell culture applications, J. Mater. Chem. B 1 (2013) 987–996.

DOI: 10.1039/c2tb00019a

[5] H. Park, I. Berzin, J. De Luis, G. Vunjak-Novakovic, Evaluation of silicone tubing toxicity using tobacco BY2 culture, In Vitro Cell Dev Biol Plant. 41 (2005) 555–560.

DOI: 10.1079/ivp2005670

[6] R.M. Lycans, C.B. Higgins, M.S. Tanner, E.R. Blough, B.S. Day, Plasma treatment of PDMS for applications of in vitro motility assays, Colloids Surf. B Biointerfaces 116 (2014) 687–694.

DOI: 10.1016/j.colsurfb.2013.11.007

[7] P. Hron, Hydrophilisation of silicone rubber for medical applications, Polym. Int. 52 (2003) 1531–1539.

DOI: 10.1002/pi.1273

[8] D.G. Castner, B.D. Ratner, Biomedical surface science: Foundations to frontiers, Surf. Sci. 500 (2002) 28–60.

DOI: 10.1016/s0039-6028(01)01587-4

[9] L.A. Bloomfield, Primer system for bonding conventional adhesives and coatings to silicone rubber, Int. J. Adhes. Adhes. 68 (2016) 239–247.

DOI: 10.1016/j.ijadhadh.2016.04.001

[10] M. Khorasani, S. MoemenBellah, H. Mirzadeh, B. Sadatnia, Effect of surface charge and hydrophobicity of polyurethanes and silicone rubbers on L929 cells response, Colloids Surf. B: Biointerfaces 51 (2006) 112–119.

DOI: 10.1016/j.colsurfb.2006.06.002

[11] H.M. Tan, H. Fukuda, T. Akagi, T. Ichiki, Surface modification of poly(dimethylsiloxane) for controlling biological cells' adhesion using a scanning radical microjet, Thin Solid Films 515 (2007) 5172–5178.

DOI: 10.1016/j.tsf.2006.10.026

[12] C. Boudot, M. Kühn, M. Kühn-Kauffeldt, J. Schein, Vacuum arc plasma deposition of thin titanium dioxide films on silicone elastomer as a functional coating for medical applications, Mater. Sci. Eng. C 74 (2017) 508–514.

DOI: 10.1016/j.msec.2016.12.045

[13] T. Okada, Y. Ikada, Surface modification of silicone for percutaneous implantation, J. Biomater. Sci. Polym. Ed. 7 (1996) 171–180.

[14] S. Sugiura, J.I. Edahiro, K. Sumaru, T. Kanamori, Surface modification of polydimethylsiloxane with photo-grafted poly (ethylene glycol) for micropatterned protein adsorption and cell adhesion, Colloids Surf. B: Biointerfaces 63 (2008) 301–305.

DOI: 10.1016/j.colsurfb.2007.12.013

[15] P. Liu, Q. Chen, B. Yuan, M. Chen, S. Wu, S. Lin, J. Shen, Facile surface modification of silicone rubber with zwitterionic polymers for improving blood compatibility, Mater. Sci. Eng. C 33 (2013) 3865–3874.

DOI: 10.1016/j.msec.2013.05.025

[16] Y. Maruko, T.G.P. Galindo, M. Tagaya, Modification of Poly(dimethylsiloxane) by Mesostructured Siliceous Films for Constructing Protein-Interactive Surfaces, E-J. Surf. Sci. Nanotechnol. 16 (2018) 41–48.

DOI: 10.1380/ejssnt.2018.41

[17] L.C. Gerhardt, G.M.R. Jell, A.R. Boccaccini, Titanium dioxide (TiO2) nanoparticles filled poly (D, L lactid acid)(PDLLA) matrix composites for bone tissue engineering, J. Mater. Sci. Mater. Med. 18 (2007) 1287–1298.

DOI: 10.1007/s10856-006-0062-5

[18] R. Adell, B. Eriksson, U. Lekholm, P.I. Brånemark, T. Jemt, Long-term follow-up study of osseointegrated implants in the treatment of totally edentulous jaws, Int J Oral Maxillofac Implants 5 1990(1990) 347–359.

DOI: 10.1016/s0300-9785(81)80077-4

[19] T.Albrektsson, P.I. Branemark, H.A. Hansson, J. Lindstrom, Osseointegrated titanium implants: Requirements for ensuring a long-lasting, direct bone-to-implant anchorage in man, Acta Orthop. Scand. 52 (1981)155–170.

DOI: 10.3109/17453678108991776

[20] O. Girshevitz, Y. Nitzan, C.N. Sukenik, Solution-deposited amorphous titanium dioxide on silicone rubber: a conformal, crack-free antibacterial coating, Chem. Mater. 20 (2008) 1390‒1396.

DOI: 10.1021/cm702209r

[21] H. Yamamoto, Y. Shibata, T. Miyazaki, Anode glow discharge plasma treatment of titanium plates facilitates adsorption of extracellular matrix proteins to the plates, J. Dent. Res. 84 (2005) 668–671.

DOI: 10.1177/154405910508400717

[22] Y. Shibata, Y. Tanimoto, A review of improved fixation methods for dental implants. Part I: Surface optimization for rapid osseointegration, J. Prosthodont. Res. 59 (2015) 20–33.

DOI: 10.1016/j.jpor.2014.11.007

[23] Jeom Sik Song, Sukmin Lee, Gook Chan Cha, Journal of applied polymer science 2005; 96: 1095‒1101. J.S. Song, S. Lee, G.C. Cha, S. H. Jung, S.Y. Choi, K.H. Kim, M.S. Mun, Surface modification of silicone rubber by ion beam assisted deposition (IBAD) for improved biocompatibility, J. Appl. Polym. Sci. 96 (2005).

DOI: 10.1002/app.21530

[24] H. Liu, T.J. Webster, Nanomedicine for implants: a review of studies and necessary experimental tools, Biomaterials 28 (2007) 354–369.

DOI: 10.1016/j.biomaterials.2006.08.049

[25] K. Shiba, T. Kataoka, M. Okuda, S. Blanco-Canosa, M. Tagaya, Designed synthesis of well-defined titania/iron (III) acetylacetonate nanohybrids with magnetic/luminescent properties, RSC Adv. 6 (2016) 55750–55754.

DOI: 10.1039/c6ra03824g

[26] T. Kokubo, H. Takadama, How useful is SBF in predicting in vivo bone bioactivity?, Biomaterials. 27 (2006) 2907–2915.

DOI: 10.1016/j.biomaterials.2006.01.017

[27] Y. Chai, T. Yamaguchi, M. Tagaya, Fabrication of phospholipid vesicle-interacted calcium phosphate films with sterilization stability, Cryst. Growth. Des. 17 (2017) 4977–4983.

DOI: 10.1021/acs.cgd.7b00918

[28] D. Buso, J. Pacifico, A. Martucci, P. Mulvaney, Gold‐Nanoparticle‐Doped TiO2 Semiconductor Thin Films: Optical Characterization. Adv. Funct. Mater. 17 (2007) 347–354.

DOI: 10.1002/adfm.200600349

[29] S. Bhattacharya, A. Datta, J.M. Berg, S. Gangopadhyay, Studies on surface wettability of poly (dimethyl) siloxane (PDMS) and glass under oxygen-plasma treatment and correlation with bond strength, J. Microelectromech. S. 14 (2005) 590–597.

DOI: 10.1109/jmems.2005.844746

[30] D. Bodas, C. Khan-Malek, Formation of more stable hydrophilic surfaces of PDMS by plasma and chemical treatments, Microelectron Eng. 83(2006) 1277–1279.

DOI: 10.1016/j.mee.2006.01.195

[31] H. Zhang, J.F. Banfield, Kinetics of crystallization and crystal growth of nanocrystalline anatase in nanometer-sized amorphous titania, Chem. Mater. 14 (2002) 4145–4154.

DOI: 10.1021/cm020072k

[32] F. Balas, M. Kawashita, T. Nakamura, T. Kokubo, Formation of bone-like apatite on organic polymers treated with a silane-coupling agent and a titania solution, Biomaterials. 27(2006) 1704–1710.

DOI: 10.1016/j.biomaterials.2005.10.004

[33] H. Jensen, A. Soloviev, Z. Li, E.G. Søgaard, XPS and FTIR investigation of the surface properties of different prepared titania nano-powders, Appl. Surf. Sci. 246 (2005) 239–249.

DOI: 10.1016/j.apsusc.2004.11.015

[34] M. Minella, M.G. Faga, V. Maurino, C. Minero, E. Pelizzetti, S. Coluccia, G. Martra, Effect of fluorination on the surface properties of titania P25 powder: an FTIR study, Langmuir. 26 (2010) 2521–2527.

DOI: 10.1021/la902807g

[35] X.X. Wang, S. Hayakawa, K. Tsuru, A. Osaka, Bioactive titania gel layers formed by chemical treatment of Ti substrate with a H2O2/HCl solution, Biomaterials. 23 (2002) 1353–1357.

DOI: 10.1016/s0142-9612(01)00254-x

[36] H. Chen, C. Wang, X. Yang, Z. Xiao, X. Zhu, K. Zhang, X. Zhang, Construction of surface HA/TiO2 coating on porous titanium scaffolds and its preliminary biological evaluation, Mater. Sci. Eng. C. 70, (2017) 1047–1056.

DOI: 10.1016/j.msec.2016.04.013

[37] D.K. Pattanayak, S. Yamaguchi, T. Matsushita, T. Nakamura, T. Kokubo, Apatite-forming ability of titanium in terms of pH of the exposed solution. J. R. Soc. Interface. (2012) 1–11.

DOI: 10.1098/rsif.2012.0107

[38] J. Locs, I. Narkevica, L. Bugovecka, J. Ozolins, L. Berzina-Cimdina, Apatite-forming ability of thermally treated titania with various phase compositions. Mater. Lett. 146 (2015) 69–72.

DOI: 10.1016/j.matlet.2015.01.129

[39] M. Uchida, H.M. Kim, T. Kokubo, S. Fujibayashi, T. Nakamura, Structural dependence of apatite formation on titania gels in a simulated body fluid, J. Biomed. Mate.r Res. A. 64 (2003) 164–170.

DOI: 10.1002/jbm.a.10414

[40] Y.W. Gu, B.Y. Tay, C.S. Lim, M.S. Yong, Biomimetic deposition of apatite coating on surface-modified NiTi alloy, Biomaterials, 26 (2005) 6916–6923.

DOI: 10.1016/j.biomaterials.2005.04.051

[41] X.X. Wang, S. Hayakawa, K. Tsuru, A. Osaka, A comparative study of in vitro apatite deposition on heat‐, H2O2‐, and NaOH‐treated titanium surfaces, J. Biomed. Mate.r Res. A. 54 (2001) 172–178.

DOI: 10.1002/1097-4636(200102)54:2<172::aid-jbm3>3.0.co;2-#

[42] J.M. Wu, M. Wang, Y.W. Li, F.D. Zhao, X.J. Ding, A. Osaka, Crystallization of amorphous titania gel by hot water aging and induction of in vitro apatite formation by crystallized titania, Surf. Coat. Technol. 201 (2006) 755–761.

DOI: 10.1016/j.surfcoat.2005.12.025

[43] M. Uchida, H.M. Kim, T. Kokubo, T. Nakamura, Apatite-forming ability of sodium-containing titania gels in a simulated body fluid, J. Am. Ceram. Soc. 84 (2001) 2969–2974.

DOI: 10.1111/j.1151-2916.2001.tb01122.x