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HomeKey Engineering MaterialsKey Engineering Materials Vol. 782Fabrication of Novel Hemostatic Film with Oxidized...

Fabrication of Novel Hemostatic Film with Oxidized Cellulose and Sugar-Containing Hydroxyapatite

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Abstract:

The novel hemostatic film for the surgery of bone diseases was fabricated using TEMPO(2,2,6,6-tetramethylpiperidine-1-oxyl)-oxidized cellulose nanofibers (TOCNs), and phosphoryl oligosaccharides of calcium (POs-Ca) or sugar-containing hydroxyapatite (s-Ca₁₀(PO₄)₆(OH)₂; s-HAp). Three kinds of the hydrophilic and transparent films with the thicknesses of 10 to 20 μm were fabricated, i.e., TOCN, POs-Ca-added TOCN and s-HAp-added TOCN films. Among these films, the uptake amount of the simulated body fluid by s-HAp-added TOCN film was as high as 5,543%, which was expected to quickly stop bleeding of larger amount of blood for the hemostasis.

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Periodical:

Key Engineering Materials (Volume 782)

Pages:

84-90

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.782.84

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Online since:

October 2018

Authors:

Yeon Jeong Noh, Tomohiro Umeda, Yoshiro Musha, Kiyoshi Itatani*

Keywords:

Hemostatic Film, Hydroxyapatite, Oxidized Cellulose, Sugar

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© 2018 Trans Tech Publications Ltd. All Rights Reserved

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