The Research Progress of Fluorescent Probes for Detection of Selenols

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Selenols (R-SeH) are similar to thiols , both of them are important reducing substance. Selenocysteine (Sec) and hydrogen selenide (H2Se) are two important selenols. They play a key role in cancer research and disease treatment. Recently, fluorescent probes and nanoprobes for detecting selenols have been developed rapidly because that fluorescent methods can be applied for biological imaging of cells or in vivo. Therefore, it is very important to the detect selenols. In this paper, we summarized the fluorescent probes for detecting the selenols in recent years.

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315-319

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September 2020

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© 2020 Trans Tech Publications Ltd. All Rights Reserved

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[1] J. T. Rotruck, A. L. Pope, H. E. Ganther, A. B. Swanson, D. G. Hafeman , W. G Hoekstra, Selenium: biochemical role as a component of glutathione peroxidasec. Nutrition Reviews, 1980.38(8), 280-283.

DOI: 10.1111/j.1753-4887.1980.tb05961.x

Google Scholar

[2] C. Jacob, G. I. Giles, N. M. Giles, H. Sies, Sulfur and selenium: the role of oxidation state in protein structure and function.. Angewandte Chemie International Edition, 2003, 42(39): 4742-4758.

DOI: 10.1002/anie.200300573

Google Scholar

[3] Baker, Monya. Whole-animal imaging: The whole picture. Nature, 2010, 463, 977-980.

Google Scholar

[4] F.P. Kong, B. Hu, Y. Gao, X.H. Pan,, F. Huang, Q. Zheng, H. Chen, B. Tang, Fluorescence imaging of selenol in HepG2 cell apoptosis induced by Na2SeO3, Chem. Commun. 2015, 51, 3102-3105.

DOI: 10.1039/c4cc06359g

Google Scholar

[5] B. Hu, R. R. Cheng, X. Gao, X.H. Pan, F. P. Kong, K. H. Xu and B. Tang, Targetable mesoporous silica nanoprobes for mapping the subcellular distribution of H2Se in cancer cells. Appl. Mater. Interfaces 2018. 10, 20, 17345-17351.

DOI: 10.1021/acsami.8b02206

Google Scholar

[6] F. P. Kong, Y. H. Zhao, Z. Y. Liang, X. J., X. H. Pan, D. R. Luan, K. H. Xu, and B. Tang. A Highly Selective Fluorescent Probe for Imaging H2Se in Living cells and in vivo Based on the Disulfide Bond, Analytical Chemistry. 89(1):688-693.

DOI: 10.1021/acs.analchem.6b03136

Google Scholar

[7] H. Maeda, K. Katayama, H. Matsuno, T. Uno. 3'-(2,4-Dinitrobenzenesulfonyl) -2',7'-dimethyl-fluorescein as a fluorescent probe for selenols. Angew. Chem. Int. Ed. 2006, 45, 1810-1813.

DOI: 10.1002/anie.200504299

Google Scholar

[8] Y. X. Nan, W. J. Zhao, X.H. Xu, C. T. Au, R.H. Qiu, Synthesis, characterization and applications of selenocysteine responsive nanoprobe based on dinitrobenzene sulfonyl-modified poly(carbonate)s micelles. RSC Advances.2015, 5(85), 69299-69306.

DOI: 10.1039/c5ra12314c

Google Scholar

[9] B. X. Zhang, C. P. Ge, J. Yao, Y. P. Liu, H.C. Xie, and J.G. Fang, Selective selenol fluorescent probes: design, synthesis, structural determinants, and biological applications. J. Am. Chem. Soc. 2015, 137, 757-769.

DOI: 10.1021/ja5099676

Google Scholar

[10] C. G. Dai, J.L. Wang, Q. H. Song, Red fluorescent probes based on a BODIPY analogue for selective and sensitive detection of selenols in solutions and in living systems. J. Mater. Chem. B.2016,4, 6726-6733.

DOI: 10.1039/c6tb02081j

Google Scholar

[11] Q. Sun, S. H. Yang, L. Wu, Q.J. Dong, W. C. Yang, and G. F. Yang, Detection of intracellular selenol-containing molecules using a fluorescent probe with near-zero background signal, Anal. Chem. 2016,88, 6084-6091.

DOI: 10.1021/acs.analchem.6b01545

Google Scholar

[12] Q. Wang, S. R. Zhang, Y.G. Zhong, X. F. Yang, Z. Li, and H. Li, Preparation of yellow-green-emissive carbon dots and their application in constructing a fluorescent turn-on nanoprobe for Imaging of selenol in living cells. Anal. Chem. 2017, 89, 1734−1741.

DOI: 10.1021/acs.analchem.6b03983

Google Scholar