Biocompatibility and Mechanical Properties Evaluation of Ti-6Al-4V Lattice Structures with Varying Porosities

Abstract:

Ti-6Al-4V is one of the popular choices for biomedical implants due to multiple advantages, such as corrosion resistance, high strength-to-weight ratio, biocompatibility, lightweight, durability, and osseointegration properties. However, Young’s modulus (E) of Ti-6Al-4V is much higher than the E of natural human bone, which may lead to stress shielding. Therefore, it is critical that we need to fabricate the implant with specific mechanical properties that can match the patient’s existing bone. With the advent of 3D printing, we now can design porous structures with the most suitable E through adjusting porosity to suit individual needs. Porous structures with various porosities were manufactured by selective laser melting (SLM). Mechanical testing was performed to show that the E of the printed samples was related to the porosities only. Based on the simulated and actual results, there are still many areas that can be improved to enhance the quality of the printed structures. Indirect cytotoxicity tests were performed to verify the biocompatibility of the porous structures.

• Periodical: Key Engineering Materials (Volume 923)
• Pages: 21-29
• DOI: https://doi.org/10.4028/p-64o0e4
• Online since: June 2022
• Authors: Niyou Wang*, S. Thameem Dheen, Jerry Ying Hsi Fuh, Senthil Kumar Anantharajan
• Keywords: Cytotoxicity, Lattice Structure, Mechanical Property, Ti6Al4V, Young's Modulus

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