Synthesis and Characterization of Silica Coated Magnetite Nanoparticle Clusters for Viral RNA Extraction

Sabah Zaman; Imran Nazir; Zulfiqar Khattak; Rashida Abbasi; Amjad Ali

doi:10.4028/p-c26no6

Paper Titles

Comparative Studies on the Electrical Properties of PEDOT:PSS Doped SNP Films and Hydrogels for Medical Electrode Applications
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Study on the Surface Area of Electrospun Magnesium Oxide (MgO) Nanofibers
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Surface Characterization of Lüders Band on NiTi Shape Memory Alloy
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Effect of Sericin Additive on Cellulose Acetate Membrane Morphology and Protein Rejection
p.65

Synthesis and Characterization of Silica Coated Magnetite Nanoparticle Clusters for Viral RNA Extraction
p.71

Fabrication and Pulse Sequences Evaluation of Iron Oxides Nanoparticles as MRI Contrast Agent
p.79

Synthesis of Silver Nanoclusters from Melia azedarach and their Usage for Catalytic Degradation of Variable Organic Dyes
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Effect of Bracket Width on Bending Deformation of NiTi Arch Wire: A Finite Element Study
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A Review of Characterizing Methods for Carbonation in Cement-Based Materials
p.105

HomeKey Engineering MaterialsKey Engineering Materials Vol. 929Synthesis and Characterization of Silica Coated...

Synthesis and Characterization of Silica Coated Magnetite Nanoparticle Clusters for Viral RNA Extraction

Abstract:

Magnetite nanoparticles or iron oxide nanoparticles are the most explored magnetic nanoparticles till recent times, particularly due to their attractive properties for biomedical applications such as viral RNA extraction. The physical and chemical properties of magnetite nanoparticles and their clusters largely depend on the synthesis method and chemical structure. Co-precipitation method was used to synthesize magnetite nanoparticles at varying process parameters. The nanoparticles were coated with silicon-oxide using Stober method at different deposition durations. These particles were characterized by X-Ray Diffraction, Scanning Electron Microscopy, vibrating sample Magnetometer and PCR testing to study the phases formed, morphology, size, magnetic properties and RNA extraction efficiency. The synthesized magnetite nanoparticles were in the range of 10 to 100 nm; suitable for super-para-magnetic behavior. The maximum saturation magnetization achieved for synthesized paramagnetic beads was 56 emu and RNA extraction efficiency was more than 80% as compared to commercial beads.

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Periodical:

Key Engineering Materials (Volume 929)

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71-77

DOI:

https://doi.org/10.4028/p-c26no6

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Online since:

August 2022

Authors:

Sabah Zaman*, Imran Nazir, Zulfiqar Khattak, Rashida Abbasi, Amjad Ali

Keywords:

Covid-19 Testing, Magnetite Nanoparticles, RNA Detection, Silica Coated Nanobeads

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