A Swelling Study in Different PH and Mechanical Properties of Biodegradable Films Based on Pluronic F-127/ Poly-Vinyl Alcohol

Article Preview

Abstract:

PluronicF-127/PVA polymeric biomaterials blend films plasticized with glycerin were prepared by solvent molding method. The polymer blend films were characterized using Fourier transform infrared (FTIR) spectroscopy, Field Emission Scanning Electron Microscopy and mechanical measurements. The FTIR spectra of the two polymers and their blends show that there is no chemical interaction between the PVA and the PluronicF-127. FESEM images indicate that blend homogeneous film can easily be prepared. Mechanical and swelling properties of the studied blends indicate that these can be used for medical application such as biodegradable materials and biodegradable drugs carriers and as food packaging materials.

You might also be interested in these eBooks

Info:

Periodical:

Materials Science Forum (Volume 1002)

Pages:

389-398

Citation:

Online since:

July 2020

Authors:

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2020 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

* - Corresponding Author

[1] N. Tudorachi, C.N. Cascaval, M. Rusu, M. Pruteanu, Testing of polyvinyl alcohol and starch mixtures as biodegradable polymeric materials,, Polym. Testing 19 (2000) 785-799.

DOI: 10.1016/s0142-9418(99)00049-5

Google Scholar

[2] Lijun Mao, Syed Imam, Sherald Gordon, Patrizia Cinelli, and Emo Chiellini, Extruded Cornstarch–Glycerol–Polyvinyl Alcohol Blends: Mechanical Properties, Morphology, and Biodegradability,, J. of Polymers and the Environment 8 (2000) 205-211.

DOI: 10.1023/a:1015201928153

Google Scholar

[3] J. H. Song, R. J. Murphy, R. Narayan, and G. B. H. Davies, Biodegradable and compostable alternatives to conventional plastics,, Philos. Trans R Soc. Lond B Biol. Sci. 364 (2009) 2127-2139.

DOI: 10.1098/rstb.2008.0289

Google Scholar

[4] N. M. Yanina, P. Lucrecia, R. C. Guillermo and D. B. Javier,Polyvinyl Alcohol–Pectin Cryogel Films for Controlled Release of Enrofloxacin,, Appl. Biochem. Biotechnol. 167 (2012) 1421-1429.

DOI: 10.1007/s12010-012-9554-6

Google Scholar

[5] J. Dutta, Synthesis and Characterization of γ-irradiated PVA/PEG/CaCl2 Hydrogel for Wound Dressing,, American J. of Chem. 2 (2012) 6-11.

Google Scholar

[6] F. Febriyenti, F. Najmiatul, M. Noratiqah, U. Salman, N. Deni, R. Shintia and B. S. Bin, Honey gel and film for burn wound,, Inter. J. of Drug Delivery. 6 (2014) 01-06.

Google Scholar

[7] J. Jun, L. Chunhua, L. Jack, C. H. Ralph R. Basil, R. H. Miriam and S. C. Jonathan, The effect of physiologically relevant additives on the rheological properties of concentrated Pluronic copolymer gels,, Polymer. 49 (2008) 3561-3567.

DOI: 10.1016/j.polymer.2008.05.038

Google Scholar

[8] J. J. Escobar-Chávez, M. López-Cervantes, A. Naïk, Y. N. Kalia, D. Quintanar-Guerrero, A. Ganem-Quintanar, Applications of Thermo-reversible PluronicF-127 gels in Pharmaceutical Formulations,, J. Pharm Pharmaceut. Sci. 9 (2006) 339-358.

DOI: 10.1080/10837450600940824

Google Scholar

[9] D. Jain, E. Carvalho, A. K. Banthia and R. Banerjee. Development of polyvinyl alcohol–gelatin membranes for antibiotic delivery in the eye,. Drug Development and Indus. Pharm. 37 (2011) 167-177.

DOI: 10.3109/03639045.2010.502533

Google Scholar

[10] T. M. P. Le, V. P. Pham, T. M. L. Dang, T. H. La, T. H. Le and Q. H. Le, Preparation of curcumin-loaded pluronic F127/chitosan nanoparticles for cancer therapy,, Adv. Nat. Sci.: Nanosci. Nanotechnol. 4 (2013) 025001.

DOI: 10.1088/2043-6262/4/2/025001

Google Scholar

[11] M. L. Sanyang, S. M. Sapuan,  M. Jawaid, M. R. Ishak, and J. Sahari, Effect of plasticizer type and concentration on physical properties of biodegradable films based on sugar palm (arenga pinnata) starch for food packaging,, J. Food Sci. Technol. 53 (2016) 326-336.

DOI: 10.1007/s13197-015-2009-7

Google Scholar

[12] S. Khairunnisa, J. Zahidah and I. Rostini, The effect of glycerol concentration as a plasticizer on edible films made from alginate towards its physical characteristic,, WSN 112 (2018) 130-141.E.

Google Scholar

[13] S. Balakrishnan,‏ P. Santhanam, and M. Srinivasan, Larvicidal potency of marine actinobacteria isolated from mangrove environment against Aedes aegypti and Anopheles stephensi,, J. Parasit Dis. 41(2017) 387-394.

DOI: 10.1007/s12639-016-0812-3

Google Scholar

[14] J. S. Zainab Al-Lami and A. M. Haddad, Preparation and swelling behavior of L-lactide interpenetrating,, Open Journal of Organic Polymer Materials 6 (2016) 119-133.

DOI: 10.4236/ojopm.2016.64012

Google Scholar

[15] X. Pan, J. Li, R. Gan and X. Hu, Preparation and in vitro evaluation of enteric-coated tablets of rosiglitazone sodium,, Saudi Pharm J. 23 (2015) 581-586.

DOI: 10.1016/j.jsps.2015.02.018

Google Scholar