Preliminary Studies on Antimicrobial Properties for Nanofiber Air Filters

Abstract:

The purpose of this study was to investigate a potential antimicrobial activity of biodegradable cellulose acetate (CA)/ cetylpyridinium bromide (CPB) nanofiber filters produced by electrospinning technique. Samples of these nanofibers were produced over a nonwoven substrate, using a polymeric solution in the electrospinning process. Wettability tests were performed by measuring the contact angle of droplets of water deposited on their surface. The evaluation of the antibacterial properties of the nanofibers was performed for Escherichia coli using quantitative methods. Regarding the contact angle measurement, it presented about 63o, showing that this material can be wetted by water. The antibacterial test results showed that the use of the surfactant provides antibacterial properties to the CA/CPB nanofibers, presenting 100% reduction for bacteria. Further studies are necessary, however, these preliminary results showed that, based on these features, the nanofibers could be applied as a filter media for indoor air conditioning systems, mainly due to their biocidal properties.

• Periodical: Materials Science Forum (Volume 1063)
• Pages: 57-62
• DOI: https://doi.org/10.4028/p-wykmip
• Online since: June 2022
• Authors: Fabio A.P. Scacchetti*, Daniela S. de Almeida, Roberta Santos, Marcos H. S. Santana, Fabrício M. Bezerra, Mônica Lopes Aguiar, Leila D. Martins
• Keywords: Antimicrobial Activity, Electrospinning Process, Nanofibers

References

[1] U. Habiba, A.M. Afifi, A. Salleh, e B.C. Ang, Chitosan/(polyvinyl alcohol)/zeolite electrospun composite nanofibrous membrane for adsorption of Cr6+, Fe3+ and Ni2+,, J. Hazard. Mater., vol. 322, p.182–194, jan. 2017,.

DOI: 10.1016/j.jhazmat.2016.06.028

[2] Q. Wang, D.-G. Yu, L.-L. Zhang, X.-K. Liu, Y.-C. Deng, e M. Zhao, Electrospun hypromellose-based hydrophilic composites for rapid dissolution of poorly water-soluble drug,, Carbohydr. Polym., vol. 174, p.617–625, out. 2017,.

DOI: 10.1016/j.carbpol.2017.06.075

[3] S. Kendouli et al., Modification of cellulose acetate nanofibers with PVP/Ag addition,, Mater. Sci. Semicond. Process., vol. 28, p.13–19, dez. 2014,.

[4] A. Ali et al., Antibacterial electrospun nanomat from nigella/PVA system embedded with silver,, J. Text. Inst., vol. 112, no 4, p.561–567, abr. 2021,.

DOI: 10.1080/00405000.2020.1768015

[5] C. Kriegel, K.M. Kit, D. J. McClements, e J. Weiss, Influence of Surfactant Type and Concentration on Electrospinning of Chitosan–Poly(Ethylene Oxide) Blend Nanofibers,, Food Biophys., vol. 4, no 3, p.213–228, set. 2009,.

DOI: 10.1007/s11483-009-9119-6

[6] W. Zuo, M. Zhu, W. Yang, H. Yu, Y. Chen, e Y. Zhang, Experimental study on relationship between jet instability and formation of beaded fibers during electrospinning,, Polym. Eng. Sci., vol. 45, no 5, p.704–709, 2005,.

DOI: 10.1002/pen.20304

[7] T. Lin, H. Wang, H. Wang, e X. Wang, The charge effect of cationic surfactants on the elimination of fibre beads in the electrospinning of polystyrene,, Nanotechnology, vol. 15, no 9, p.1375–1381, ago. 2004,.

DOI: 10.1088/0957-4484/15/9/044

[8] Q.P. Pham, U. Sharma, e A. G. Mikos, Electrospinning of polymeric nanofibers for tissue engineering applications: a review,, Tissue Eng., vol. 12, no 5, p.1197–1211, maio 2006,.

DOI: 10.1089/ten.2006.12.1197

[9] S. Mohanan et al., Role of Quaternary Ammonium Compounds and ATMP on Biocidal Effect and Corrosion Inhibition of Mild Steel and Copper,, Corros. Rev., vol. 23, no 4-5–6, p.425–444, dez. 2005,.

DOI: 10.1515/corrrev.2005.23.4-5-6.425

[10] M. Lukáč et al., Synthesis, self-aggregation and biological properties of alkylphosphocholine and alkylphosphohomocholine derivatives of cetyltrimethylammonium bromide, cetylpyridinium bromide, benzalkonium bromide (C16) and benzethonium chloride,, Eur. J. Med. Chem., vol. 66, p.46–55, ago. 2013,.

DOI: 10.1016/j.ejmech.2013.05.033

[11] J.G. Lundin, P.N. Coneski, P.A. Fulmer, e J.H. Wynne, Relationship between surface concentration of amphiphilic quaternary ammonium biocides in electrospun polymer fibers and biocidal activity,, React. Funct. Polym., vol.77, p.39–46, abr. 2014, doi:10.1016/ j.reactfunctpolym.2014.02.004.

DOI: 10.1016/j.reactfunctpolym.2014.02.004

[12] L.J. del Valle et al., Electrospun biodegradable polymers loaded with bactericide agents,, AIMS Mol. Sci., vol. 3, no 1, p.52–87, 2016,.

[13] D. S. de Almeida et al., Development and characterization of electrospun cellulose acetate nanofibers modified by cationic surfactant,, Polym. Test., vol. 81, p.106206, jan. 2020,.

DOI: 10.1016/j.polymertesting.2019.106206

[14] D. S. Almeida, E. H. Duarte, L. D. Martins, E. C. Muniz, e M. L. Gimenes, Processo de Obtenção de Nanofibras a Base de Acetato de Celulose com Surfactante por Eletrofiação e Nanofibras Obtidas,, BR102019019386.

DOI: 10.47749/t/unicamp.2020.1128970

[15] B. J. Ryan e K. M. Poduska, Roughness effects on contact angle measurements,, Am. J. Phys., vol. 76, no 11, p.1074–1077, nov. 2008,.

DOI: 10.1119/1.2952446

[16] S. Buffet-Bataillon, P. Tattevin, M. Bonnaure-Mallet, e A. Jolivet-Gougeon, Emergence of resistance to antibacterial agents: the role of quaternary ammonium compounds—a critical review,, Int. J. Antimicrob. Agents, vol. 39, no 5, p.381–389, maio 2012,.

DOI: 10.1016/j.ijantimicag.2012.01.011

[17] N.A.N.N. Malek e N.I. Ramli, Characterization and antibacterial activity of cetylpyridinium bromide (CPB) immobilized on kaolinite with different CPB loadings,, Appl. Clay Sci., vol. 109–110, p.8–14, jun. 2015,.

DOI: 10.1016/j.clay.2015.03.007