The reciprocating corrosion wear behavior of a nickel-free austenitic stainless steel 13Cr24Mn0.44N flat against a Si3N4 ceramic counter ball was investigated in two kinds of aqueous such as artificial body solution and distilled water by using the ball-on-flat configuration with 300 μm amplitude at various normal loads. The worn surfaces of the new stainless steel were observed by scanning electron microscopy (SEM). Elements valence in wear scars were also detected by X-ray photoelectron spectroscopy (XPS). The influences of the load and aqueous media on the friction coefficient and wear resistance of the new stainless steel were analyzed. It is clear that the friction coefficient decreased in both aqueous with the load increasing. The lubricative surface film formed on the wear scars in the artificial body solution could reduce the friction coefficient, and result in a lower wear loss in the artificial body solution than that in the distilled water, which demonstrates a negative interactive effect between wear and corrosion.