Effect of the Surface Energy on the Biomineralization Behavior and Cell Compatibility of Carbonated Hydroxyapatite

Abstract:

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Carbonated hydroxyapatite (CHA) and hydroxyapatite (HA) were prepared by the wet chemical method. The contact angle was measured to calculate the surface energy. The biomineralization process in SBF solution of HA and CHA were investigated in vitro. The cell attachment and proliferation behavior of CHA and HA were compared by the cell culture experiments. The results show that the polar component of surface energy of B-type CHA is higher than that of HA. Osteoblastic cells attach and proliferate very well on the surface, which indicates the excellent cell compatibility. The CHA have high bioactivity owing to rapid formation of hydroxyl-carbonate-apatite (HCA) mineralized layer on the biomaterial’s surface in SBF.

Info:

Periodical:

Materials Science Forum (Volumes 610-613)

Main Theme:

Edited by:

Zhong Wei Gu, Yafang Han, Fu Sheng Pan, Xitao Wang, Duan Weng and Shaoxiong Zhou

Pages:

1203-1207

DOI:

10.4028/www.scientific.net/MSF.610-613.1203

Citation:

Q. X. Zhu et al., "Effect of the Surface Energy on the Biomineralization Behavior and Cell Compatibility of Carbonated Hydroxyapatite", Materials Science Forum, Vols. 610-613, pp. 1203-1207, 2009

Online since:

January 2009

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$35.00

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