Protein Adsorption Behaviors on PLLA Surface Studied by Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D)

Rong Zeng; Yi Zhang; Mei Tu; Chang Ren Zhou

doi:10.4028/www.scientific.net/MSF.610-613.1219

Paper Titles

Effect of the Surface Energy on the Biomineralization Behavior and Cell Compatibility of Carbonated Hydroxyapatite
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Ring Opening Polymerization of ε-Caprolactone Catalyzed with Magnesium Lactate
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Ti-Glass Biocomposite Coating Materials and their Crystallization Dynamics
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Study on the Hemolysis Rate and Cytotoxicity Test of Porous Ultramicron HA Containing Mg
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Protein Adsorption Behaviors on PLLA Surface Studied by Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D)
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Gradient Rare-Earths Bioceramic Composite Coating Fabricated by Wide-Band Laser Cladding and its Bioactivity
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Improved HA Coating on Titanium Substrate Using Induction Heating and Hydrothermal Treatment Methods
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Preparation and Characteristics of Gradient Silk Fibroin/Hydroxyapatite Porous Composites
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Study on Preparation and Properties of Nitric Oxide Releasing Polyurethane
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Protein Adsorption Behaviors on PLLA Surface Studied by Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D)

Abstract:

The adsorption of two different proteins (bovine serum albumin (BSA) and collagen-I) onto poly (L-lactic acid) (PLLA) surface was investigated using quartz crystal microbalance with dissipation monitoring (QCM-D) and atomic force microscopy (AFM). It’s found that protein characteristics would greatly affect the adsorption kinetics, structure and viscoelastic properties of adsorbed protein layers. Compared with BSA, collagen-I trended to form a loose, dissipative layer with a slower adsorption rate and larger adsorption reversibility, which is consistent with AFM observation. The results provided some valuable information for controlling the structure and properties of adsorbed proteins to develop an alternative surface-modification approach for biomaterials.