In Vitro Cytocompatibility of Silver-Containing Hydroxyapatite Coatings

Abstract:

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In this paper, antibacterial silver-containing hydroxyapatite coating was prepared by vacuum plasma spraying method and osteoblasts were seeded onto the surface of the coating to evaluate its cytocompatibility. The results indicated that the cells proliferated well on the samples, and the proliferation rate on the silver-containing hydroxyapatite coating was a little bit higher than that on the silver-free hydroxyapatite coating. The contact angle of water drop on the coating was measured, and it was found that the contact angles of the silver-containing hydroxyapatite coatings were smaller than the hydroxyapatite coating. The improvement of hydrophilicity for the silver-containing hydroxyapatite coating could be beneficial to the cells proliferation on its surface. It can be concluded that the addition of silver in the hydroxyapatite coating endowed the coating with antibacterial property while maintaining its excellent cytocompatibility.

Info:

Periodical:

Materials Science Forum (Volumes 620-622)

Edited by:

Hyungsun Kim, JienFeng Yang, Tohru Sekino and Soo Wohn Lee

Pages:

567-570

DOI:

10.4028/www.scientific.net/MSF.620-622.567

Citation:

Y. K. Chen et al., "In Vitro Cytocompatibility of Silver-Containing Hydroxyapatite Coatings", Materials Science Forum, Vols. 620-622, pp. 567-570, 2009

Online since:

April 2009

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Price:

$35.00

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