Biomimetic and Smart Polymeric Surfaces for Biomedical and Biotechnological Applications

Abstract:

Surfaces and biointerfaces are recurrent when materials are used in bio-related applications. Bio-inspired concepts have been implemented in this field and gained increasing interest. In this context, stimuli-responsive surfaces have found applicability in a variety of subjects, including switchable surfaces to control protein immobilization or cell adhesion, porous membranes for controlled drug delivery applications, substrates and scaffolds for tissue engineering applications, biosensors, or membranes for bioseparation. Moreover, self-assembly strategies and hierarchical structures often found in Nature could inspire scientist and engineers to propose new solutions in the design and fabrication of surfaces with special features, such as wettability within extreme ranges, improved adhesion, optical and mechanical properties and specific bioactivity. In this work some aspects related to the use of stimuli-responsive and biomimetic surfaces in the field of biomedicine and biotechnology are highlighted and some examples are presented.

• Periodical: Materials Science Forum (Volumes 636-637)
• Pages: 3-8
• DOI: https://doi.org/10.4028/www.scientific.net/MSF.636-637.3
• Online since: January 2010
• Authors: João F. Mano
• Keywords: Biomaterial, Biomedicine, Patterning, Polymeric Surface, Stimuli-Responsive

References

[1] J. Aizenberg and P. Fratzl: Adv. Mater. Vol. 4 (2009), p.387.

[2] H. Shin, S. Jo and A.G. Mikos: Biomaterials Vol. 24 (2003), p.4353.

[3] Y.N. Xia and G.M. Whitesides: Ann. Rev. Mater. Sci. Vol. 28 (1998), p.153.

[4] A. Bernard, E. Delamarche, H. Schmid, B. Michel, H.R. Bosshard and H. Biebuyck: Langmuir Vol. 14 (1998), p.2225.

DOI: 10.1021/la980037l

[5] Z.H. Nie and E. Kumacheva: Nature Materials Vol. 7 (2008), p.277.

[6] M.S. Kim, G. Khang and H. Bang: Prog. Polym. Sci. Vol. 33 (2008), p.138.

[7] E. Costa Martínez, J.C. Rodríguez Hernández, M. Machado, J.F. Mano, J.L. Gómez Ribelles, M. Monleón Pradas and M. Salmerón Sánchez: Tissue Engineering A Vol. 14 (2008), p.1751.

[8] J.F. Mano: Adv. Eng. Mater. Vol. 10 (2008), p.515.

[9] P.M. Mendes: Chem. Soc. Rev. Vol. 37 (2008), p.2512.

[10] K. Uchida, K. Sakai, E. Ito, O. H. Kwon, A. Kikuchi, M. Yamato and T. Okano: Biomaterials Vol. 21 (2000), p.923.

[11] M. Yamato, Y. Akiyama, J. Kobayashi, J. Yang, A. Kikuchi and T. Okano: Prog. Polym. Sci. Vol. 32 (2007), p.1123.

[12] R. M. P. da Silva, J. F. Mano and R. L. Reis: Trend in Biotech. Vol. 25 (2007), p.577.

[13] R. M. P. da Silva, P. M. López-Perez, C. Elvira, J. F. Mano, J. San Róman and R. L. Reis: Biotechn. and Bioeng. Vol. 101 (2008), p.1321.

[14] A. Garcia, M. Marquez, T. Cai, R. Rosário, Z. Hu, D. Gust, M. Hayes, S. A. Vail and C. -D. Park: Langmuir Vol. 23 (2007), p.224.

[15] J. Shi, N. M. Alves and J. F. Mano: Adv. Funct. Mater. Vol. 17 (2007), p.3312.

[16] C.I. Dias, J.F. Mano and N.M. Alves: J. Mater. Chem. Vol. 18 (2008), p.2493.

[17] G.M. Luz and J.F. Mano: Phil. Trans. R. Soc. A, Vol. 367 (2009), p.1587.

[18] Z. Hong, R.L. Reis and J.F. Mano: Acta Biomater. Vol. 4 (2008) p.1297.

[19] Z. Hong, R.L. Reis and J.F. Mano: J. Biomed. Mater. Res. A Vol. 88A (2009), p.304.

[20] D.S. Couto, N.M. Alves, J.F. Mano: J. Nanosci. Nanotech. Vol. 9 (2009) p.1741.

[21] T.L. Sun, L. Feng, X.F. Gao and L. Jiang: Acc. Chem. Res. Vol. 38 (2005), p.644.

[22] N. J. Shirtcliffe, G. McHale, M. I. Newton, G. Chabrol and C. C. Perry: Adv. Mater. Vol. 16 (2004), p. (1929).

[23] J. Shi, N. M. Alves and J. F. Mano: Biosinsp. & Biomim. Vol. 3 (2008) p.1.

[24] N.M. Alves, J. Shi, E. Oramas, J.L. Santos, H. Tomás and J.F. Mano: J. Biomed. Mater. Res. A, in press.

[25] W. Song, D.D. Veiga, C.A. Custódio and J.F. Mano: Adv. Mater., Vol. 21 (2009) p.1830.