A Novel Biodegradable Multichamber Microstructure for Implantable Drug Controlled Release

Abstract:

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The research work reported in this paper design a novel biodegradable multichamber microstructure for implantable drug controlled release by introducing the approach of topology optimization. It is therefore highly desirable to overcome these restrictions that pre-defined topology of the device result in difficulty to obtain a linear or pulsed drug release profile. The designed biodegradable multichamber microstructure is fabricated using UV-LIGA microfabrication and Micro-molding technique. The simulation results show that the multichamber microstructure exhibits a preferable linear drug release profile.

Info:

Periodical:

Materials Science Forum (Volumes 654-656)

Main Theme:

Edited by:

Jian-Feng Nie and Allan Morton

Pages:

2269-2272

DOI:

10.4028/www.scientific.net/MSF.654-656.2269

Citation:

R. X. Yu et al., "A Novel Biodegradable Multichamber Microstructure for Implantable Drug Controlled Release", Materials Science Forum, Vols. 654-656, pp. 2269-2272, 2010

Online since:

June 2010

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Price:

$35.00

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