Nano-Hardness Testing of Wear Particles in Sheep Knee Joints

Christopher Allen; Zhong Xiao Peng; Ling Yin; Emma Carmichael

doi:10.4028/www.scientific.net/MSF.654-656.2253

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Nano-Hardness Testing of Wear Particles in Sheep Knee Joints
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HomeMaterials Science ForumMaterials Science Forum Vols. 654-656Nano-Hardness Testing of Wear Particles in Sheep...

Nano-Hardness Testing of Wear Particles in Sheep Knee Joints

Abstract:

This work aimed to establish a suitable procedure for establishing wear particle hardness and to investigate if the hardness of articular cartilage wear particles increases with increasing grades of osteoarthritis. To achieve the goals a selection of fresh sheep knee joints were obtained and consequently worn in a specially designed wear simulator. Wear particles were then removed from the joint using a syringe and prepared for hardness testing. In order to test the hardness of the wear particle samples nanoindentation was used. Once completed statistical analyses and correlation analyses were performed in order to find any relationships present. This was the first time that the hardness of the wear particles was tested and studied. As a result of the tests performed a general relationship between wear particle hardness and osteoarthritis grade was able to be determined. It was also determined that further work needed to be conducted on the experimental procedure to increase the accuracy of the results obtained.

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Periodical:

Materials Science Forum (Volumes 654-656)

Pages:

2253-2256

DOI:

https://doi.org/10.4028/www.scientific.net/MSF.654-656.2253

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Online since:

June 2010

Authors:

Christopher Allen, Zhong Xiao Peng, Ling Yin, Emma Carmichael

Keywords:

Articular Cartilage, Nano-Hardness Testing, Sheep Knee Joint, Wear Particle

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References

[1] R.L. Drake, et al., Gray's Anatomy for Students. 2005, Canada: Elsevier Inc. pp.38-39, p.532539.

Google Scholar

[2] E.N. Marieb and K. Hoehn, Human Anatomy and Physiology. 7 ed. 2007, San Franciso: Pearson Benjamin Cummins. pp.273-274.

Google Scholar

[3] Rush University Medical Center. Arthrits & Other Rheumatic Diseases. [cited 2009 14. 3]; Available from: http: /www. rush. edu/rumc/page-1098987342230. html.

Google Scholar

[4] Z. Peng, Wear, 2006: pp.630-641.

Google Scholar

[5] J.S. Stecki and M.L.S. Anderson, Bull. of the CMCM (Monash University) 3 1 (1991), p.9. 19. 10.

Google Scholar

[6] R.A. Bank, et al., Arthritis and Rheumatism, 2000. 43(10): pp.2202-2210.

Google Scholar

[7] T. Franz, et al., Osteoarthritis and Cartilage, 2001. 9: pp.582-592.

Google Scholar

[8] M.L. Oyen, Journal of Biomechanics, 2006. 39: pp.2699-2702.

Google Scholar

[9] M.P. Groover, Fundamentals of Modern Manufacturing. 2007, New Jersey: John Wiley and Sons Inc. pp.51-56.

Google Scholar

[10] O. Franke, et al., Acta Biomaterialia, 2007. 3: pp.873-881.

Google Scholar