Luminous Chitosan-Dye Nanocomposite Particles with Enhanced Lifetime and Stability

Article Preview

Abstract:

Nanoparticular chitosan-dye nanocomposites were prepared by a facile ionotropic gelation, which show a much improved stability against UV and ozone attack. The nanocomposites do not contain any toxic material. Also, as natural occurring biopolymeric chitosan is used as the matrix material, the nanocomposite is biocompatible and biodegradable with high bioaffinity. After suitable bioconjugation, the developed luminous chitosan-dye nanocomposites can be used as target biolabels in various medical and biomedical applications.

You might also be interested in these eBooks

Info:

Periodical:

Pages:

87-93

Citation:

Online since:

June 2012

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2012 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

[1] X. Michalet, F. F. Pinaud, L. A. Bentolila, J. M. Tsay, S. Doose, J. J. Li, G. Sundaresan, A. M. Wu, S. S. Gambhir and S. Weiss: Science Vol. 307 (2005), p.538.

DOI: 10.1126/science.1104274

Google Scholar

[2] J. Jang, J. Bae and E. Park: Adv. Functi. Mater. Vol. 16 (2006), p.1400.

Google Scholar

[3] M. De, P. S. Ghosh and V. M. Rotello: Adv. Mater. Vol. 20 (2008), p.4225.

Google Scholar

[4] J. H. Ho, L. Gu, G. von Maltzahn, E. Ruoslahti, S. N. Bhatia and M. J. Sailor: Nat. Mater. Vol. 8 (2009), p.331.

Google Scholar

[5] P. Sharma, S. C. Brown, A. Singh, N. Iwakuma, G. Pyrgiotakis, V. Krishna, J. N. Knapik, K. Barr, B. M. Moudgil and S. R. Grobmyer: J. Mater. Chem. Vol. 20 (2010), p.8128.

DOI: 10.1039/c0jm00354a

Google Scholar

[6] Z. A. Peng and X. G. Peng: J. Am. Chem. Soc. Vol. 123 (2001), p.183.

Google Scholar

[7] K. G. Li, J. T. Chen, S. S. Bai, X. Wen, S. Y. Song, Q. Yu, J. Li and Y. Q. Wang: Toxicol in Vitro Vol. 23 (2009), p.1007.

Google Scholar

[8] L. Y. Chen, C. L. Chen, R. N. Li, Y. Li and S. Q. Liu: Chem. Commum. Vol. 19 (2009), p.2670.

Google Scholar

[9] A. M. Derfus, W. C. W. Chan and S. N. Bhatia: Nano Lett. Vol. 4 (2004), p.11.

Google Scholar

[10] S. B. Park, J. O. You, H. Y. Park, S. J. Haam and W. S. Kim: Biomaterials Vol. 22 (2001) p.323.

Google Scholar

[11] T. Suzuki, T. Matsumoto, Y. Hagino, in: Science and Technology of Polymers and Advanced Materials, edited by P. N. Prasad, J. E. Mark, S. H. Kandil, Z. H. Kafafi, Plenum, New York (1998).

Google Scholar

[12] P. J. VandeVord, H. W. T. Matthew, S. P. DeSilva, L. Mayton, B. Wu and P. H. Wooley: J. Biomed. Mater. Res. Vol. 59 (2002), p.585.

DOI: 10.1002/jbm.1270

Google Scholar

[13] R. A. Langer: Chem. Res. Vol. 94 (2000), p.94.

Google Scholar

[14] J. Berger, M. Reist, J. M. Mayer, O. Felt, N. A. Peppas and R. Gurny: Euro. J. Pharm. Biopharm. Vol. 57 (2004), p.19.

Google Scholar

[15] For example: L. Ma and C. S. Liu: Colloids Surf. B: Biointerf. Vol. 75 (2010), p.448.

Google Scholar

[16] For example: A. CooperN. Bhattarai, F. M. Kievit, M. Rossoi and M. Zhang: Phys. Chem. Chem. Phys. Vol. 13 (2011), p.9969.

Google Scholar

[17] J. M. Gong, X. L. Hu, K. W. Wong, Z. Zheng, L. Yang, W. M. Lau and R. Du: Adv. Mater. Vol. 20 (2008), p.2111.

Google Scholar

[18] J. M. Gong, Z. J. Zhou, X. L. Hu, M. K. Wong, K. W. Wong and Z. L. Du: ACS Appl. Mater. Interfaces Vol. 1 (2009), p.26.

Google Scholar