Preparation and Characterization of Magnetic Carbonate Apatite/Chitosan/Alginate Composite Scaffold

Abstract:

Treatment for bone cancer has begun to be experimented with ferrimagnetic for magnetic induction hyperthermia. On the other hand, composites of bioceramics and biopolymer have been studied for scaffold as these materials resemble the structure of bone. The current study investigated the magnetization of calcium aluminum ferrite magnetic (CaAl₄Fe₈O₁₉) incorporated in carbonate apatite, alginate and chitosan, that serves as a scaffold. CaAl₄Fe₈O₁₉ powder were synthesized using calcium nitrate, aluminium nitrate and ferrous chloride using the sol-gel method. Combining the carbonate apatite/chitosan/alginate compoiste and CaAl₄Fe₈O₁₉ using the freeze-dry method has produced carbonate apatite/alginate/chitosan/CaAl₄Fe₈O₁₉ composite scaffolds. The CaAl₄Fe₈O₁₉ powder and the scaffolds were observed using SEM (scanning electrone microscope) and their magnetization were measured using VSM (vibrating sample magnetometer). It was shown that the scaffold is a composite structure of CaAl₄Fe₈O₁₉ particles, having diameter ranging from 0.5 to 2 µm, embedded in the pore walls of the carbonate apatite/alginate/chitosan matrix. The saturation magnetization Ms and remanence magnetization Mr of the CaAl₄Fe₈O₁₉ particles were 20 and 2.0 emu/g, whereas, those of the magnetic scaffold were 4.3 and 2.0 emu/gr. The addition of the carbonate apatite/alginate/chitosan composite into CaAl₄Fe₈O₁₉ decreased the fraction and/or magnetic of the CaAl₄Fe₈O₁₉ particles.

• Periodical: Materials Science Forum (Volume 827)
• Pages: 75-80
• DOI: https://doi.org/10.4028/www.scientific.net/MSF.827.75
• Online since: August 2015
• Authors: Decky Jusiana Indrani*, Bambang Sunendar Purwasasmita, Ari Adi Wisnu, Jojor Simanjuntak
• Keywords: Carbonate Apatite, Hysteresis Curve, Magnetic, Scaffold

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