Occupational Safety and Health Risk Assessment in Engineered Nanoparticles Manufacturing Processes

Abstract:

The engineered nanoparticles are more and more entering in Romanian working places, both in research laboratories and in manufacturing processes. Ever increasingly numerous evidence shows that this materials science revolution can generate significant health, safety and environmental hazards, in addition to the social, economic and ethical challenges involvedBased on the precautionary principle recommended be the European Union and a thorough literature review, this research is intended to introduce a framework for further development of an Occupational Health and Safety risk management foundation in this field of concern. Starting from a systematic approach in terms of occupational exposure, the paper emphasizes certain feasible means aimed at nanoparticle’s risk assessment, particularly in a qualitative manner. Recommendations are provided for the industry in order to meet the safety regulations, which in turn should be adapted to the findings of researches, considering that we are facing emerging risks whose nature is often unknown.

• Periodical: Materials Science Forum (Volume 887)
• Pages: 65-73
• DOI: https://doi.org/10.4028/www.scientific.net/MSF.887.65
• Online since: March 2017
• Authors: George Bălan*, Roland Iosif Moraru, Lorena Bălan
• Keywords: Assessment, Health Risk, Nonparticle Manufacturing, Safety

References

[1] EU – OSHA, Workplace exposure to nanoparticles, European Risk Observatory, EN 2, (2009).

[2] U. Heinrich, Chronic inhalation exposure of Wistar rats and two different strains of mice to diesel engine exhaust, carbon black and titanium dioxide, Inhal. Toxicol, 7, 533-556, (1995).

DOI: 10.3109/08958379509015211

[3] D.L. Huber, Synthesis, properties, and applications of iron nanoparticles, Small, 1, , 482-501, (2005).

[4] L.I. Cioca, R.I. Moraru, Nanosafety (in Romanian), Editura Universităţii"Lucian Blaga", Sibiu, (2011).

[5] G. Oberdorster, Toxicology of ultrafine particles: In vivo studies, Philos. Trans. R. Soc. Londra , pag. 2719-2740, (2000).

[6] G. Oberdörster, E. Oberdörster, J. Oberdörster, Nanotoxicology: an ermerging discipline evolving from studies of ultrafine particles, Environ Health Perspect, 173-179 (2005).

DOI: 10.1289/ehp.7339

[7] A.D. Maynard, R.J. Aikten, Assessing exposure to airborne nanomaterials : Current abilities and future requirements, Nanotoxicology, 1, 26-41, (2007).

DOI: 10.1080/17435390701314720

[8] T.P. Kauppinen, Assessment of exposure in occupational epidemiology. Scand. J. Work Environ. Health, 20, 19-29, (1994).

[9] R.I. Moraru, G.B. BăbuţOccupational risk of engineered nanoparticles: assessment and prevention - control measures, Quality - Acces to success, 14, 96-100 (2013).

[10] A.D. Maynard, E.D. Kuempel, Airborne nanostructured particles and occupational health, Journal of Nanoparticle Research, 7, 587-614 (2005).

DOI: 10.1007/s11051-005-6770-9

[11] C.M. Sayes, K.L. Reed, D.B. Warheit, Assessing toxicity of fine and nanoparticles: comparing in vitro measurements to in vivo pulmonary toxicity profiles, Toxicological Sciences, 97, 163-180, (2007).

DOI: 10.1093/toxsci/kfm018

[12] S.Y. Paik, D.M. Zalk, P. Swuste, Application of a pilot control banding tool for risk assessment and control of nanoparticle exposures . Ann Occup Hyg 52 (6) : 419-428.

[13] N. Lewinski, V. Colvin, R. Drezek, Cytotoxicity of nanoparticles, Small, 4, 26-49, (2008).

DOI: 10.1002/smll.200700595

[14] P.A. Valberg, C.M. Long, S.N. Sax, Integrating studies on carcinogenic risk of carbon black: epidemiology, animal exposures, and mechanism of action, J Occup Environ Med, 48, 1291-1307, (2006).

DOI: 10.1097/01.jom.0000215342.52699.2a