Biocompatibility of Titanium Carbo-Nitride Coatings with Fetal Rat Calvarial Cells

Ji Eun Kim; Young Gon Sun; Jong Wook Moon; Xing Hui Piao; Young Jun Kim

doi:10.4028/www.scientific.net/MSF.904.85

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Biocompatibility of Titanium Carbo-Nitride Coatings with Fetal Rat Calvarial Cells
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HomeMaterials Science ForumMaterials Science Forum Vol. 904Biocompatibility of Titanium Carbo-Nitride...

Biocompatibility of Titanium Carbo-Nitride Coatings with Fetal Rat Calvarial Cells

Abstract:

Surface modification is a promising technique to improve mechanical properties of titanium and titanium alloys by changing the surface composition or microstructures. In this study, titanium carbo-nitride coating had been deposited on Ti-6Al-4V alloy by arc ion plating. The biocompatibility of TiN and TiCN coating on Ti-6Al-4V alloy with fetal rat calvarial cells was assessed by Enzyme Linked Immunoabsorbent Assay (ELISA) and Alkaline phosphatase (ALPase) activity. The effect of surface coating on IL-1β and IL-6 production was determined by ELISA. On IL-1β and IL-6 production, there were no statistical difference between control and thin coating surfaces. After 7 days of culture, the cells were provided to measure ALPase activity. ALPase activity of cells cultured on TiN and TiCN surface was similar to that seen on cp-Ti.

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Periodical:

Materials Science Forum (Volume 904)

Pages:

85-89

DOI:

https://doi.org/10.4028/www.scientific.net/MSF.904.85

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Online since:

August 2017

Authors:

Ji Eun Kim*, Young Gon Sun, Jong Wook Moon, Xing Hui Piao, Young Jun Kim

Keywords:

Biocompatibility, Rat Calvarial Cells, Titanium Carbo-Nitride Coating

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