Easy Preparation of Bacterial Cellulose/Triamcinolone Acetonide Composites and their Inhibition for Fibroblasts

Abstract:

Wound healing is accompanied by keloids, it is important to develop a wound dressing which can inhibit keloid and relieve pain and pruritus in patients. In this paper, bacterial cellulose/triamcinolone acetonide (BC/TA) composites are prepared by easy solution impregnation method, which the structures of BC/TA composites were analyzed by fourier transform infrared spectroscopy (FTIR). The drug release and inhibition of L929 cells were also analyzed. It can be concluded that BC/TA composites have a sustained release effect on TA and can effectively inhibit proliferation of L929 in the range of 0.5-2.0 mg/cm².

• Periodical: Materials Science Forum (Volume 913)
• Pages: 707-713
• DOI: https://doi.org/10.4028/www.scientific.net/MSF.913.707
• Online since: February 2018
• Authors: Miao Ying Jin, Shi Yan Chen*, Bao Xiu Wang, Hua Ping Wang
• Keywords: BC/TA Composites, Drug Release, Inhibition

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