Model of Controlled Drug Release from the Polymer Implant

L.A. Komar; A.L. Svistkov; A.V. Kondyurin

doi:10.4028/www.scientific.net/MSF.938.139

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HomeMaterials Science ForumMaterials Science Forum Vol. 938Model of Controlled Drug Release from the Polymer...

Model of Controlled Drug Release from the Polymer Implant

Abstract:

A mathematical model for analysis of features of the drug release , previously introduced into a polymer implant, into a biological tissue is proposed. A carbon nanolayer obtained as a result of plasma-immersion ion implantation was created to improve biocompatibility with biological tissue on the surface of the implant. The medicine can go through micro-ruptures in this layer. Calculations show that the carbon layer allows a uniform release of the drug.

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Periodical:

Materials Science Forum (Volume 938)

Pages:

139-147

DOI:

https://doi.org/10.4028/www.scientific.net/MSF.938.139

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Online since:

October 2018

Authors:

L.A. Komar*, A.L. Svistkov, A.V. Kondyurin

Keywords:

Chemical Potential, Controlled Release, Diffusion, Drug, Implant, Mathematical Model, Polymer

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* - Corresponding Author

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