The Preparation of Fluorescent Nano Dye-Silica Particles by Sol-Gel Process

Young Joo Na; Sang Joon Park; Ji Hyeon Kim; Jong Sung Kim

doi:10.4028/www.scientific.net/SSP.124-126.651

Paper Titles

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Sol-Gel Synthesis of GdAlO₃ Buffer Layers on SrTiO₃ (100) Substrates
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The Preparation of Fluorescent Nano Dye-Silica Particles by Sol-Gel Process
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Electrical Properties BaTiO₃ Thick Films with an Interlayer SrTiO₃ Thin Films
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Structural and Dielectric Properties of Screen Printed PZT(70/30) Multilayered Thick Films
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Effect of Catalyst on the Colloidal Silica Particle Growth in Direct Oxidation of Silicon
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The Preparation of Fluorescent Nano Dye-Silica Particles by Sol-Gel Process

Abstract:

The core-shell structure of dye-silica nanoparticle has been prepared. The dye-silica nanoparticle can be used as a substitute of fluorescent dye for bio analysis. The hybrid organicinorganic nanoparticle was prepared by sol-gel process using organic modified silane as the coupling agent for flourescent dye and silica. The size of the particle was about 50 nm, which was measured by DLS and confirmed by SEM photograph. The fluorescent dye (fluorescein-5-maleimide) was reacted with (3-mercaptopropyl) trimethoxy silane to produce dye-silane compound, followed by the sol-gel reaction with tetraethoxysilane(TEOS) and water to produce core-shell structure. The fluorescent spectrum showed that the fluorescent intensity of dye-silica nanoparticle was higher than that of fluorescent dye.