Influence of Poly(Ethylene Oxide) on the Processability of Xanthan Gum via Hot Melt Extrusion

Conor Coffey; Joshua H. Yoon; Luke M. Geever

doi:10.4028/www.scientific.net/AMM.679.57

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HomeApplied Mechanics and MaterialsApplied Mechanics and Materials Vol. 679Influence of Poly(Ethylene Oxide) on the...

Influence of Poly(Ethylene Oxide) on the Processability of Xanthan Gum via Hot Melt Extrusion

Abstract:

In this study, xanthan gum and poly (ethylene oxide) (PEO) were blended via hot melt extrusion. Results showed that PEO acted as a plasticiser and lowered the melt viscosity of xanthan gum/PEO blends. For example, melt flow rate and torque level were observed to decrease at increasing percent compositions of PEO in the blend. Breakdown testing demonstrated that xanthan gum accelerates the breakdown rates compared to the breakdown rate of 100 % PEO extrudate samples.

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Periodical:

Applied Mechanics and Materials (Volume 679)

Pages:

57-62

DOI:

https://doi.org/10.4028/www.scientific.net/AMM.679.57

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Online since:

October 2014

Authors:

Conor Coffey, Joshua H. Yoon, Luke M. Geever

Keywords:

Drug Delivery, Hot Melt Extrusion, Melt Flow Rate, Poly (Ethylene Oxide), Xanthan Gum

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References

[1] L. Li, O. AbuBaker, and Z. Shao. Drug. Dev. Ind. Pharm. Vol. 32 (2006), pp.991-1002.

Google Scholar

[2] P.K. Mididoddi and M.A. Repka. Eur. J. Pharm. Biopharm. Vol. 66 (2007), pp.95-105.

Google Scholar

[3] N. E Harding, J.E. Cleary and L. Lelpi in: Genetics and Biochemistry of Xanthan gum production by xanthomonas campestris, editied by Y. H. Hui and G. G. Khachatourians, 1st Edition, Food Biotechnology: Microorganisms, Chapter 12, John Wiley & Sons, (1995).

Google Scholar

[4] R.C. Mundargi, S.A. Patil, and T.M. Aminabhavi. Carbohyd. poly. Vol. 69 (2007), pp.130-141.

Google Scholar

[5] I. Babla, P. Yeole, P. Nakhat, and U. Galgatte. Indian. J. Pharm. Sci. Vol. 68 (2006), pp.185-189.

DOI: 10.4103/0250-474x.25712

Google Scholar

[6] S. Shah, S. Maddineni, J. Lu, and M.A. Repka. Int. J. Pharm, Vol. 453 (2013), pp.233-252.

Google Scholar

[7] E. Kenny, D. Devine, C. Higginbotham, and L. Geever. Journal of Asian Scientific Research Vol. 3 (2013), pp.654-669.

Google Scholar

[8] M.M. Crowley, F. Zhang, J.J. Koleng, and J.W. McGinity. Biomaterials. Vol. 23 (2002) pp.4241-4248.

DOI: 10.1016/s0142-9612(02)00187-4

Google Scholar

[9] E. Verhoeven, C. Vervaet, and J.P. Remon. Eur. J. Pharm. Biopharm. Vol. 63 (2006), pp.320-330.

Google Scholar