Applied Mechanics and Materials Vol. 730

Abstract: In this study, the biotransformation which from cortisone acetate (CA) to prednisone acetate (PA) by Arthrobacter simplex (ASP) was selected as a model system for evaluating the effects of natural cyclodextrins (α-CD, β-CD and γ-CD, referred as CDs) on cell growth, dehydrogenase activity, permeability of Arthrobacter simplex. The results showed that the cavity size of cyclodextrins on ASP cell growth were quite different, the with smaller cavity significantly inhibited ASP growth. CDs reduced the dehydrogenase activity of ASP and increased the cell permeability. Initial conversion rate of cells after treated by CDs were higher than the control cells. The study provided basic datas for the application of cyclodextrin in the steroid biotransformation.

Abstract: The focus of the study was to establish an UPLC-ESI-MS/MS method for the qualitative and quantitative determination of VLPVPR in rat plasma. The method was as follows: Protein impurities in the rat plasma samples were precipitated with methanol; A Waters Acquity BEH C18 column (100 mm×2.1 mm, 1.7 μm) was adopted; the column temperature was 25°C; the mobile phase consisted of methanol-water with gradient elution at the steady flow rate of 0.3 mL·min-1; the detection wavelength was 202 nm. Mass spectrometry applied selected ion monitoring mode with m/z 255 (quantitative ion) and m/z 169 (qualitative ion). It was found that excellent linear relationship was obtained from the range of 10~200 ng·mL-1 (r=0.9991), the limit determination (LOD) of VLPVPR was 1.8 ng·mL-1, the recovery rate was 96.33%~100.76%, The inter and intre-day RSD were less than 7%. We thus conclude that a rapid and sensitive UPLC-ESI-MS/MS method was developed and validated for the determination of recombinant antihypertensive peptide VLPVPR in rat plasma. It can be applied to evaluate the pharmacokinetics of VLPVPR.

Abstract: This study used two types of plant, eucalyptus and bamboo, to produce sorbents for copper (II), cadmium (II), zinc (II), and lead (II) metal ion removal in a water bath shake. The porous biomorphic-genetic composite of hydroxyapatite/carbon with eucalyptus template (PBGC-Fe/C-E) and the porous biomorphic-genetic composite of hydroxyapatite/carbon with bamboo template (PBGC-Fe/C-B) were prepared using eucalyptus and bamboo as plant templates, and through various processes including ammonia leaching, cyclical impregnation using calcium hydroxide and diammonium solutions, and aerobic firing inside muffle furnaces. Tests were conducted on the HAP/C composites to observe their adsorption effects on Cu (II), Zn (II), Pb (II), and Cd (II). The results show that the prepared composites were able to adsorb heavy metals in water effectively. The results indicated that the adsorbed amount of PBGC-Fe/C-E were found to be 16.4371, 4.6725,24.5528, 17.0194 mg/1 for Cu (II), Zn (II), Pb (II) and Cd (II) ions at initial concentration of 50mg/L (25°C), respectively. The adsorbed amount of PBGC-Fe/C-B were found to be 10.5876, 3.9142,21.2463, 13.4721 mg/1 for Cu (II), Zn (II), Pb (II) and Cd (II) ions at initial concentration of 50mg/L (25°C), respectively. The prepared adsorbent is expected to be a new material for the removal of heavy metals from contaminated water.

Abstract: In recent years, the expansion of marine oil and gas transport has led to the increase of oil spill accidents. Both accidents occurring in deep sea and coastal regions can bring huge financial losses. As the development of ocean model, oil spill model has been proposed and became a valid countermeasure to simulate the process of transport, diffusion and transformation of the surface oil in seawater. This paper presents an oil spill model with a novel cross-platform (Windows/Linux) architecture. This model can not only compute oil concentration mathematically and numerically, but also can draw oil spill concentration maps with pseudo color, by using computer visualization technique. The tendency of transport, diffusion and transformation of oil could be illustrated in chronological order by the concentration maps. Furthermore, an oil spill simulation case has been accomplished, and the simulation results is discussed in this paper. Results showed that this model could simulate oil slick motions effectively and had friendly user interface.

Abstract: In urban sludge and sawdust as raw material,using zinc chloride activation method in the preparation of activated carbon under different operating conditions, through the detection of specific surface area activated carbon sample and methylene blue adsorption value and the iodine adsorption value, studies the impregnation ratio, activation time and activation temperature operating conditions affect the performance of activated carbon sample. Through to the physical and chemical modification of activated carbon,To the preparation of activated carbon adsorption purification treatment experiment was carried out in the discharge of sewage.

Abstract: The performance comparisons of engine fueled with butanol/gasoline and ethanol/gasoline blends were tested. It was indicated from the experimental results that, compared with pure gasoline, power and fuel economy of engine fueled with butanol/gasoline and ethanol/gasoline blends reduced slightly, while HC and CO emission reduced significantly, and NO emission increased. It can be concluded that, the performance of engine fueled with butanol/gasoline blends was better than ethanol/gasoline blends, and B20 was better than B30.

Abstract: The performance of engine fueled with biodiesel was tested. It was indicated from the experimental results that NOx emission of biodiesel reduced significantly with decreasing fuel delivery advance angle BTDC, while soot emission also reduced when the fuel delivery timing was retarded for 2°CA, and the starting position of heat release rate retarded with the delay of fuel delivery timing. It can be concluded that, retarding fuel delivery timing was an effective method to reduce the NOx emission of engine fueled with biodiesel, but led to reduce the brake power output slightly.

Abstract: The performance of engine fueled with diesel/biodiesel blends was tested. It was indicated from the experimental results that the brake power, torque out and brake specific fuel consumption of engine fueled with diesel/biodiesel caused slight variations, while NOx emission increased significantly compared with engine fueled with diesel. In order to reduce NOx emission of engine fueled with pure biodiesel, retarding fuel delivery advance angle was used, and the NOx emission tests revealed that the NOx emission decreased significantly at different engine speeds.

Abstract: A multi-body simulation approximate model of a vehicle using ADAMS/CAR software is established. According to the experimental evaluation criteria and methods related to vehicle steering stability of the country, conducting the steering transient test, the steering back to positive Experimental as well as the Sine - Swept steering simulation. Exploring a parametric design method for vehicle handling stability ADAMS / CAR to analyze

Abstract: In accordance to the drawback of amphibious vehicle's low speed in water, a new kind of folding mechanism based on double wishbone suspension is proposed. Referring to the working conditions of the wheel lifted mechanism, the hydraulic circuit, which provides with the functions of pressure limiting, locked and pressure retaining, is designed to ensure the accuracy of wheel lifted and the driving safety. The appropriate hydraulic cylinders, hydraulic components and auxiliary components are chosen due to the hydraulic system load and the maximum flow rate.