Facile Synthesis of Symmetrical Homonucleotides of Antiviral Nucleosides

Jian Sun; Shan Shan Gong; Qi Sun

doi:10.4028/www.scientific.net/AMR.1046.96

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Facile Synthesis of Symmetrical Homonucleotides of Antiviral Nucleosides
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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 1046Facile Synthesis of Symmetrical Homonucleotides of...

Facile Synthesis of Symmetrical Homonucleotides of Antiviral Nucleosides

Abstract:

A facile method for the one-pot preparation of homodinucleotides of AZT and d4T from corresponding nucleoside 5′-phosphoropiperidates with 4,5-dicyanoimidazole (DCI) as the activator has been developed.

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Periodical:

Advanced Materials Research (Volume 1046)

Pages:

96-99

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.1046.96

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Online since:

October 2014

Authors:

Jian Sun, Shan Shan Gong, Qi Sun*

Keywords:

DCI, Homodinucleotides, Phosphoropiperidate, Stavudine, Zidovudine

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References

[1] R.K. Robins, Med. Res. Rev. Vol. 3 (1985) p.273.

Google Scholar

[2] R.J. Jones, N. Bischofberger, Antiviral Res. Vol. 27 (1995) p.1.

Google Scholar

[3] E. de Clercq, J. Pharmacol. Exp. Ther., Vol. 297 (2001), p.1.

Google Scholar

[4] B. Oberg, Antivir. Res., Vol. 71 (2006), p.90.

Google Scholar

[5] M. Baba, R. Pauwels, P. Herdewijn, E. De Clercq, J. Desmyter, M. Vandeputte, Biochem. Biophys. Res. Commun., Vol. 142 (1987), p.128.

Google Scholar

[6] K. Wright, Nature, Vol. 323 (1986), p.283.

Google Scholar

[7] M. Mauro, C. Anna, F. Alessandra, B. Giorgio, G. Sandra, W. Rosamund, G. Marco, D. Gianluca, F. de Antonio, B. Umberto, Proc. Natl. Acad. Sci., Vol. 93 (1996), p.4403.

Google Scholar

[8] L. Rossi, S. Serafini, P. Franchetti, Curr. Med. Chem. Anti-infect. Agents, Vol. 4 (2005), p.37.

Google Scholar

[9] S. Q. Yang, C. Pannecouque, P. Herdewijn, Chem. Biodiv., Vol. 9 (2012), p.2186.

Google Scholar

[10] Y. Ahmadibeni, K. Parang, Org. Lett., Vol. 7 (2005), p.5589.

Google Scholar

[11] Q. Sun, S. Liu, J. Sun, S. Gong, Chinese Chem. Lett., Vol. 25 (2014), p.427.

Google Scholar

[12] Q. Sun, S. Gong, S. Liu, J. Sun, G. Liu, Tetrahedron lett., Vol. 55 (2014), p.2114.

Google Scholar