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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 1073-1076Development of a High-Throughput Immunoassay for...

Development of a High-Throughput Immunoassay for Rapid Detection of Multiple Antibiotic Residues in Cosmetics

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Abstract:

Antibiotic residues in cosmetics can cause seriously healthy problems such as sensitization, systemic toxicity, or even death. The developments of rapid methods for multiple antibiotics detection are needed to conveniently detect out the illegal additives. In this study, a simple, cost-effective and time-saving immunoassay, multi-analyte dot enzyme-linked immunosorbent assay (Multi-Dot-ELISA), for the simultaneous detection of three most common abused antibiotics (CPFX, TC, and SMD) was successfully designed and developed. Based on the competitive Multi-Dot-ELISA, real samples from 5 of 15 (33%) commercial cosmetic products were found CPFX and SMD additives which are banned in China. We demonstrate that this rapid and low-cost platform is a promising tool in human health protection.

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Periodical:

Advanced Materials Research (Volumes 1073-1076)

Pages:

357-361

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.1073-1076.357

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Cite this paper

Online since:

December 2014

Authors:

Yi Ping Xun, Hai Yan, Jia Liu, Li Li Shi, Peng Chen, Hong Wu Du

Keywords:

Ciprofloxacin, Cosmetics, Multi-Dot-ELISA, Sulfametoxydiazine, Tetracycline

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© 2015 Trans Tech Publications Ltd. All Rights Reserved

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