Preparation of Bimodal Porous Biphasic Calcium Phosphate Ceramics and Their Dissolution Behavior in Simulated Body Fluid

Yin Zhang; Tetsuya Kameyama; Yoshiyuki Yokogawa

doi:10.4028/www.scientific.net/AMR.11-12.227

Paper Titles

Nano-Crystallized Glass Fibers with Second-Order Optical Nonlinearity
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Difference of Properties between Yb³⁺-Doped Silicate and Phosphate Laser Glasses
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Preparation of Red Long Afterglow Phosphorescent Material CaTiO₃: Pr³⁺
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Preparation of Macroporous Glass-Ceramic Composites Containing β-TCP
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Preparation of Bimodal Porous Biphasic Calcium Phosphate Ceramics and Their Dissolution Behavior in Simulated Body Fluid
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Particle Size Control in Sol-Gel Synthesis of Nano Hydroxyapatite
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Amorphous Calcium Silicate Coating on Metallic Titanium
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Apatite-Coated Poly(lactic acid) Composites with Cell-Compatibility Prepared by a Biomimetic Method
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PLLA/HA Electrospin Hybrid Nanofiber Scaffolds: Morphology, In Vitro Degradation and Cell Culture Potential
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Preparation of Bimodal Porous Biphasic Calcium Phosphate Ceramics and Their Dissolution Behavior in Simulated Body Fluid

Abstract:

Biphasic calcium phosphate (BCP) ceramics, a mixture of hydroxyapatite (HAp) and beta-tricalcium phosphate (β-TCP), of varying HAp/β-TCP ratios were prepared from fine powders. Porous BCP ceramic materials with HAp/β-TCP weight rations of 20/80, 40/60, and 80/20 were prepared. In this study, the bioactivity is reduced at a bigger HAp content rate, which is likely related to the high driving pore for the formation of a new phase, and the reaction rate was proportional to the β-TCP. The porous BCP ceramics having a bigger porosity rate can easily under up dissolution. The powder having a bigger β-TCP content rate can easily generate a new phase. The dissolution results confirmed that the biodegradation of calcium phosphate ceramics could be controlled by simply adjusting the amount of HAp or β-TCP in the ceramics and porosity rate.