Preparation of Bimodal Porous Biphasic Calcium Phosphate Ceramics and Their Dissolution Behavior in Simulated Body Fluid
Biphasic calcium phosphate (BCP) ceramics, a mixture of hydroxyapatite (HAp) and beta-tricalcium phosphate (β-TCP), of varying HAp/β-TCP ratios were prepared from fine powders. Porous BCP ceramic materials with HAp/β-TCP weight rations of 20/80, 40/60, and 80/20 were prepared. In this study, the bioactivity is reduced at a bigger HAp content rate, which is likely related to the high driving pore for the formation of a new phase, and the reaction rate was proportional to the β-TCP. The porous BCP ceramics having a bigger porosity rate can easily under up dissolution. The powder having a bigger β-TCP content rate can easily generate a new phase. The dissolution results confirmed that the biodegradation of calcium phosphate ceramics could be controlled by simply adjusting the amount of HAp or β-TCP in the ceramics and porosity rate.
Masayuki Nogami, Riguang Jin, Toshihiro Kasuga and Wantai Yang
Y. Zhang, T. Kameyama, Y. Yokogawa, "Preparation of Bimodal Porous Biphasic Calcium Phosphate Ceramics and Their Dissolution Behavior in Simulated Body Fluid", Advanced Materials Research, Vols. 11-12, pp. 227-230, 2006