At annealing temperature, Al-Mg alloys have grain boundary and surface magnesium segregation and their strength are also impossibly enhanced by heat treatment. Friction and wear properties of cold-rolled 5052 aluminum alloy annealed at different temperature were studied in this paper. X-ray diffract analysis(XRD) indicates that metallurgical phase has no obvious transformation with different annealing temperature. Auger electron (AE) fines that magnesium segregation and oxide layer thickness of surface are different along the plate thickness direction at different annealing temperatures. Results show that the higher oxide layer of the surface, the smaller wear can be got. Friction and wear testing shows that 5052 aluminum alloy annealed at different temperatures almost have the same coefficient of friction under the same experimental condition , but the coefficient friction of the same sample will increase while temperature rises.