A Facile Synthesis of 4-Aryl-3,4-Dihydropyrimidin-2(1H)-Ones in Iconic Liquids

Qian Shou Zong; Yang Zhang; Cheng Ping Miao; Jian Yi Wu

doi:10.4028/www.scientific.net/AMR.233-235.1023

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 233-235A Facile Synthesis of...

A Facile Synthesis of 4-Aryl-3,4-Dihydropyrimidin-2(1H)-Ones in Iconic Liquids

Abstract:

4-aryl-3,4-dihydropyrimidin-2(1H)-ones were synthesized by using Biginelli reaction in iconic liguids. The simple method provoids the title compounds in 67~97% yields by the reaction of aromaic aldehydes with aectoacetrate and urea in the presence of iconic liquids as solvent and katalyst. This method was found to be efficient way for the synthesis of 4-aryl-3,4-dihydropyrimidin-2(1H)-ones.

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Periodical:

Advanced Materials Research (Volumes 233-235)

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1023-1026

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https://doi.org/10.4028/www.scientific.net/AMR.233-235.1023

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May 2011

Authors:

Qian Shou Zong, Yang Zhang, Cheng Ping Miao, Jian Yi Wu

Keywords:

Biginelli Reaction, High Yield, Iconic Liquids

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