A Systematic Investigation on the Preparation of 2, 6-Diamino-3, 5-Dinitropyridine

Abstract:

In this paper, the preparation of 2, 6-diamino-3, 5-dinitropyridine (DADNP) were systematically investigated. The optimal method was found. The key parameters have been systematically studied, such as the synthesis route, temperature, solvent, time, the reactant ratio, and the purification route. The optimal route was confirmed and would have an important reference for pilot plant scale-up.

• Periodical: Advanced Materials Research (Volumes 236-238)
• Pages: 2299-2302
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.236-238.2299
• Online since: May 2011
• Authors: Yan Hong Wang, He Zhao, Y.D. Huang
• Keywords: DADNP, Nitration, Purification, Synthesis

References

[1] Phillip F. Pagoria, Gregory S. Lee, Alexander R. Mitchell, Robert D. Schmidt. Thermochimica Acta 384(2002), 187-204.

[2] A. K. Sikder, Nirmala Sikder. Journal of Hazardous Materials, A112(2004)，1-15.

[3] HE Zhi-wei, CHENG Jian, LIU Zu-liang. Chinese Journal of Energeic Materials, vol. 17,No. 4 (2009), 392-395.

[4] Sikkema, D. J. Polymer 39(1998), 5981–5986.

[5] G.. A.Olah, R.Malhotra, S.C. Narang, in: H. Feuer(Ed.), Nitration: methods and mechanisms, Organic Nitro Chemistry Series; VCH, New York, 1989.

[6] Hitomi Suzuki, Masao Iwaya and Tadashi Mori. Tetrahedron Letters, vol. 38. No. 32, 1997, pp.5-5650.

[7] Olah, G. A.; Olah, J.A. Overchuk, N.A. J. Org. Chem., 30,3373-3376,1965.

[8] German Patent Publication No. 3,920,336.

[9] Williams etal., J. Heterocyclic Chem.,8(1971),841-643.

[10] Ritter etal., J. Heterocyclic Chem.,32(1995), 585.

[11] Alan R. Katritzky etal. Org. Biomol. Chem. 3 (2005),538-541.