From 1997 to 2009, altogether 48059 pieces of literature on bioinformatics are extracted in SCI-Expended. Amongst them, 2853 pieces could be attributed to Chinese scholars. With NoteExpress, software that manages documents, the 48059 pieces of literature in the past 13 years were sorted using bibliometrical method. The main aim is to compare and assess the practices of bioinformatics research in China. This study examined the growth of the bioinformatics literature, in the world. The rank list was given according to different country. China’s total publication output comprises 2853 papers during the 13 years between 1997 and 2009 which was equivalent to 5.94% of the world output during the same period, and ranked the 4th. The year production and citations of papers on bioinformatics in 5 Asian countries and Taiwan district between 1997 and 2009 was compared. This study will provide general insights of bioinformatics research in China.