The coating preparation of HA on the surface of Mg-4.0Zn-1.0Ca-0.6Zr alloy sheet is carried out through a technique combining of pre-alkali-heat-solution-treatment, electro-deposition and post-alkali-heat-solution-treatment. The microstructure and appearance of the coatings are observed and analyzed by means of scan electron microscope. As well as with help of spectrophotometer, the antihemolytic ability of the alloy with HA coated in blood has been studied. The results indicate that the available ageing treatment of the alloy sheet is at 175 °C for 12 hours, and as the rule, the yield strength σ0.2 and elongation rate δ % is reached 320 MPa and 18.75 % respectively. The HA coated with a desirable microstructure is achieved under the technique parameter of the temperature 50 °C and the voltage nearly 10 V, as well as it’s ratio of Ca and P is 1.72 which is close to the human bone tissue of 1.67. The concentration of [Mg2+] in leaching liquor is depressed as the using of the alloy with HA coated so that the adverse reaction caused by higher concentration of [Mg2+] in the parts of the body position can be avoided. The value of hemolysis ratio of the alloy with HA coated is 4.06 % less than that of the alloy with un-coated which is 4.35 %, therefore the antihemolytic ability of alloy with HA coated is increased, and the phenomena of hemolysis is not taken place when it is used as one of human body planting material.