Preparation of Hydroxyapatite Powders via Neutralization Process
Hydroxyapatite (HA) and Hydroxyapatite/Chitosan (HA/CS) composite were prepared through neutralization method. The results indicate that the way of adding phosphorous acid solution is a key factor to obtain pure HA product, and that prolonged stirring time only promote the entry of CO32- into the lattice of HA crystal. The addition of chitosan can overcome those factors which hamper the formation of pure HA particles, thus optimizing the whole reaction system.
X. F. Xiao et al., "Preparation of Hydroxyapatite Powders via Neutralization Process", Advanced Materials Research, Vols. 311-313, pp. 1709-1712, 2011