Analyses of Heavy Metal Content in Different Particles Size of Centella asiatica

Abstract:

Arsenic (As), Cadmium (Cd) and Lead (Pb) are the heavy metal and categorized as high toxicity compound. This element can be found in the animal and plant from bio accumulation mechanism. This bio accumulation will lead to the toxicity when its concentration surpasses regulated value. Centella asiatica is a plant belonging to the Umbelliferae family, hydrocotyle order, which has been used for curing of venous ulcers and venous hypertension for its activity on connective tissue metabolism and endothelial integrity. This plant also widely used in formulation of drugs and cosmetic. In order to produce high quality herbal product, the characterization and standardization of heavy metal content using modern technique must be carried out. Centella asiatica nanopowders were produced at different grinding condition and analyzed for As content using ICP-OES (Optima 7300 DV, Perkin Elmer). The confirmations of size were carried out using nanoZeta Sizer S (Malvern Instrument) and Field Emission Scanning Electron Microscope. The results obtained show that As, Cd and Pb presence in all type of grinding below the acceptable daily intake by the world health organization (WHO).

• Periodical: Advanced Materials Research (Volume 364)
• Pages: 40-44
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.364.40
• Online since: October 2011
• Authors: M.Z. Borhan, R. Ahmad, Mohamad Rusop, Saifollah Abdullah
• Keywords: Centella asiatica, Heavy Metal, ICP-OES, Nanopowder

References

[1] B. Demırozu and I. Saldamlı: Turkish J. of Eng. and Env. Sciences. 26 (2002), p.361–365.

[2] Z. Krejpcıo, S. Sıonkowskı and J. Bartela: Polish Journal of Environmental Studies. 14 (2005), p.877–81.

[3] C. Cabrera, M.L. Lorenzo and M.C. Lopez: Journal of Agricultural and Food Chemistry. 43 (1995), p.1605–1609.

[4] J.M.U. Maduabuchı, C.N. Nzegwu, E.O. Adıgba, R.U. Aloke, C.N. Ezomıke, C.E. Okocha, E. Obı and O.E. Orısakwe: Science Total of Env., 366 (2006), p.621–626.

[5] K. Saha, N.H. Israf, D.A. Hamzah, A.S. Khozirah and A. Syahida: Journal of Ethnopharmacology 92 (2004), p.263–267.

DOI: 10.1016/j.jep.2004.03.007

[6] Bath, F. (2005). Consistent Milling on a Nano Scale. Application reports, cfi/Ber. DKG 82, No. 9. Available in http: /www. retsch-fr. com/fr/produits/broyer/broyeurs-planetaires-a-billes/pm-100-cm/fonction-caracteristiques/dlDetails/1/file/1526.

[7] M. He and E. Forssberg: Int. J. of Mineral Processing 84 (1-4) (2007), pp.240-251.

[8] L. Perharic, D. Shaw, M. Colbridge, I. House, C. Leon and V. Murray: Drug Saf 11(4) (1994), p.284–294.

DOI: 10.2165/00002018-199411040-00006

[9] X. Yuan, R. L. Chapman and Z. Wu, Phytochemical Analysis 22 (3) (2011), pp.189-198.

[10] J. Wu, Y. Tan, Y. Wang and R. Xu, J. of Nat. Med. 65 (3) (2011), pp.656-661.

[11] WHO, 1999. Monographs on Selected Medicinal Plants, vol. 1. World HealthOrganization, Geneva.

[12] S. B. Chen, Y. G. Zhu and Y. B. Ma, Journal of Hazardous Materials 134 (1-3) (2006), pp.74-79.

[13] J. Niu, P.E. Rasmussen, N.M. Hassan and R. Vincent: Water, Air, and Soil Pollution. 213(1-4) (2010), pp.211-25.

[14] L. Yanlong, L. Rundong, Z. Zhihui, Z. Haijun, W. Lei and L. Jingde: Intelligent Computation Technology and Automation (ICICTA), 2011 International Conference on; 2011 28-29 March 2011; 2011. pp.824-7.

[15] E.D. Caldas and L.L. Machado: Food and Chemical Toxicology 42 (2004), p.599–603.

[16] S. Albertine, M. Oetterer and L.G. Prado Filho: Boletim da SBCTA 31(1997), pp.137-147.

[17] M.J. McLaughlin, D.R. Parker and J.M. Clark: Field Crops Research 60 (1999), p.143–163.

[18] A.A. Meharg: Plant Cell Environ. 17 (1994), pp.989-993.